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U.S. Department of Health and Human Services

Drugs

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Why Learn about Adverse Drug Reactions (ADR)?

Institute of Medicine, National Academy Press, 2000
Lazarou J et al. JAMA 1998;279(15):1200–1205
Gurwitz JH et al. Am J Med 2000;109(2):87–94

 

  • Over 2 MILLION serious ADRs yearly
  • 100,000 DEATHS yearly
  • ADRs 4th leading cause of death ahead of pulmonary disease, diabetes, AIDS, pneumonia, accidents and automobile deaths
  • Ambulatory patients ADR rate—unknown
  • Nursing home patients ADR rate— 350,000 yearly

 

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