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U.S. Department of Health and Human Services

Drugs

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Drug Development and Drug Interactions: Possible Models for Decision-Making

Drug Development and Drug Interactions: Possible Models for Decision-Making

  • Possible Model for Decision Making: Metabolism-Based Drug-Drug Interaction Studies (Figures 1-4).
  • Possible Model for Decision Making: Transporter-Based Drug-Drug Interaction Studies (Figure 5)
  • Possible Models for Determining When In Vivo Transporter-Mediated Drug Interaction Studies Are Needed (Figures 6-11)
  • Possible Model for Decision Making: Therapeutic Protein-Drug Interactions (Figure 12).
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Figures

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