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U.S. Department of Health and Human Services

Animal & Veterinary

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Pre-Approval Studies in Antimicrobial Resistance and Pathogen Load

February 22-24, 2000

This workshop will be held to discuss the appropriate designs for pre-approval studies to evaluate the microbial effects of antimicrobial drugs intended for use in food-producing animals. Such studies should address the rate and extent of resistance development and changes in the number of enteric bacteria in the animal's intestinal tract that cause human illness (pathogen load). CVM seeks scientific input from experts on these issues as well as suggestions for alternative approaches.