Animal & Veterinary
Feed Grade Biuret
FDA Veterinarian Newsletter July/August 2003 Volume XVIII, No 4
On May 22, 2003, a notice was published in the Federal Register to amend the food additive regulations to provide for the safe use of feed grade biuret in lactating dairy cattle feed. Feed grade biuret is produced by the partial hydrolysis of urea and consists of a mixture of biuret, urea, cyanuric acid, and more limited amounts of triuret and other homologs.
Feed grade biuret is incorporated into animal diets as a source of non- protein nitrogen (NPN). NPN is commonly used to supplement ruminant animal diets low in protein, such as with poor quality forages. The currently approved use for feed-grade biuret in the rations of cattle as a NPN source does not provide for use in lactating dairy cattle. ADM Alliance Nutrition, Inc. submitted a food additive petition to amend the current regulation and to provide for the safe use of biuret in lactation dairy rations.
The FDA concluded that the information submitted was sufficient to establish safety and functionality for the proposed use. An environmental assessment or environmental impact statement was not required under Title 21, Code of Federal Regulations, Part 25.32(r). The food additive regulation for feed-grade biuret (21 CFR 573.220) was amended by removing paragraph (c)(1)(iii).