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U.S. Department of Health and Human Services

Animal & Veterinary

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FDA Veterinarian Newsletter November/December 1999 Volume XIV, No VI

Effective August 12, 1999, ketamine is now a Schedule III controlled substance. Increased reports of ketamine diversion and abuse, as well as a number of burglaries in veterinary clinics directed at ketamine, caused the FDA to recommend the placement into Schedule III. Veterinary groups such as the American Veterinary Medical Association, the American Animal Hospital Association, and the American Association of Equine Practitioners concurred with this recommendation. Marketed in the United States since 1971, ketamine is a rapid-acting general anesthetic used for humans and animals, but it can cause severe adverse effects including impaired memory function, dizziness, ataxia, catalepsy, hallucinations, and convulsions. The Drug Enforcement Administration (DEA) proposed the change in the FEDERAL REGISTER of April 9, 1999. Commercial containers containing ketamine must bear Schedule III labels on and after April 15, 2000