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U.S. Department of Health and Human Services

Advisory Committees

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Curriculum Vitae: Francisco Xavier Castellanos, M.D.

Francisco Xavier Castellanos, MD
215 Lexington Avenue, 14th Floor
New York, NY  10016

Education
Year Degree Field Institution
XXXX Diploma   De LaSalle High School, New Orleans, LA
XXXX A.B. Linguistics Vassar College
XXXX M. S. Experimental Psychology University of New Orleans
XXXX M.D.   Louisiana State University Medical Center

Postdoctoral Training

Internship and Residency
XXXXXXXXXXX Pediatrics, General Psychiatry and Child Psychiatry (Triple Board Program)
University of Kentucky Medical Center, Lexington, KY

Research Fellowship and Research Training
XXXXXXXXXXX Child Psychiatry Research with XXXXXXXXXXX, MD, Child Psychiatry Branch,
National Institute of Mental Health Intramural Program, Bethesda, MD
XXXXXX Short Course on Medical and Experimental Genetics,XXXXXXXXXXXXX, XXXXXXXXXXX, ME
XXXXXX Genetic Analysis of Complex Human Diseases, XXXXXXXXXXX, XXXXXXXXXXX, NC
XXXXXX Short Course on Medical and Experimental Genetics, XXXXXXXXXXX, XXXXXXXXXXX, ME

Licensure and Certification

 
XXXXXX Maryland Medical License Registration No.XXXXXXXX
XXXXXXXXXXX American Board of Pediatrics Certificate No.XXXXX
XXXXXXXXXXX American Board of Pediatrics-Recertified
XXXXXX American Board of Psychiatry and Neurology Certificate XXXXX(General Psychiatry)
XXXXXX New York State Medical License No. XXXXXXX
XXXXXXXXXXX American Board of Psychiatry and Neurology Certificate No.XXXX(Child and Adolescent Psychiatry)

Academic Appointments
1997 - 2001

Associate Professor equivalent, Child Psychiatry Branch, National Institute of
Mental Health, Bethesda, MD
2001 - Brooke and Daniel Neidich Professor of Child and Adolescent Psychiatry,
NYU School of Medicine; Tenured (2004)
2001 -

Professor of Radiology, NYU School of Medicine
2001 -

Affiliate Member, Department of Psychology, NYU
2010 -

Professor of Physiology and Neuroscience, NYU School of Medicine
2010 - Member of Neuroscience Faculty, Sackler Institute of Graduate Biomedical Sciences at NYU

Hospital Appointments
1991 - 2001 Clinical Center of the  National Institutes of Health
2002 - Tisch Hospital, NYU School of Medicine

Other Professional Positions and Visiting Appointments
1990 - 1991 Chief Resident, Triple Board Program, University of Kentucky Medical Center
1991 - 1997 Senior Staff Fellow, National Institute of Mental Health
1997 - 2001 Chief, ADHD Research Unit, National Institute of Mental Health
2001 - Founding Director, Phyllis Green and Randolph Cōwen Institute for
Pediatric Neuroscience, NYU Child Study Center
2003 - 2010 Director of Research, NYU Child Study Center
2003 - 2010 Director of Research, NYU Child Study Center
2003 -  Director of T-32 Research Training, NYU Child Study Center
2006 -  Research Psychiatrist, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY
2006 -  Director of Child and Adolescent Psychiatry Research Division, Nathan S. Kline Institute for
Psychiatric Research, Orangeburg, NY
2009 - 2014 Co-Director, NYU KL2 Translational Research Scholars Program
2010 - Vice-Chair for Research, Department of Child and Adolescent Psychiatry and NYU Child Study Center, NYU Langone
Medical Center School of Medicine

National
2002 - 2007  Member, Child Psychopathology and Developmental Disabilities Scientific Review Group;
Center for Scientific Review, National Institutes of Health4003
2003 Ad Hoc Member, National Institute on Drug Abuse Special Emphasis Panel ZDA1 EXL-T(04), Center for Scientific Review, National Institutes of Health
2004 Ad Hoc Member, Behavioral Genetics and Psychiatric Disorders Special Emphasis PanelZRG1 HOP-C (02), Center for Scientific Review, National Institutes of Health
2005 - 2007 Chair, Child Psychopathology and Developmental Disabilities Scientific Review Group;
Center for Scientific Review,
National Institutes of Health
2007 - 2012 Member, DSM-V Task Force, American Psychiatric Association
2007 - 2010 Chair, Workgroup on ADHD and Disruptive Behavior Disorders, DSM-V Task Force, American Psychiatric Association
2010 - 2013 Vice-Chair, Workgroup on ADHD and Disruptive Behavior Disorders, DSM-V Task Force, American Psychiatric    Association
2008 - 2011 Member, National Advisory Council on Drug Abuse, National Institutes of Health
2009 - 2011 Member, National Advisory Council on Drug Abuse Steering Committee

Awards and Honors
1975 Departmental Honors, Vassar College
1979 Sigma Xi Award for Original Research in Psychology
1979 Elected to membership in Sigma Xi (Honorary Psychology society)
1979 Outstanding Psychology Graduate Student, University of New Orleans
1984 - 1986 Nathaniel Bernstein Scholarship for Academic Excellence (LSUMC)
1985 Alpha Omega Alpha
1986 Chancellor's Award for Overall Excellence, LSUMC School of Medicine
1990 Travel Award Recipient, American College of Neuropsychopharmacology
1990 American Psychiatric Association's Program for Minority
Research Training in Psychiatry Mini-Fellowship
1991 Abraham Wikler, M.D. Award to the Outstanding Psychiatry Resident
1992 New Investigator's Award, New Clinical Drug Evaluation Unit (NCDEU)
1992 Fellow, American Academy of Pediatrics
1993 Award for Excellence in Clinical Care and Research, National Institute of Mental Health
1997 - 1999 Washingtonian Magazine Best Doctors
2000 CHADD Hall of Fame
2004 Teacher of the Year in Child and Adolescent Psychiatry, NYU School of Medicine
2005 Distinguished Investigator Award, National Alliance for Research in Schizophrenia and Affective Disorders (NARSAD)
2006 Blanche F. Ittleson Award for Outstanding Research in Child and Adolescent Psychiatry, American Psychiatric Association
2008 American Academy of Child and Adolescent Psychiatry Outstanding Mentor Award
2010 NeuroImage Editors’ Choice Award for Best Paper in Anatomy and Physiology

Major Committee Assignments

National
1997 - 2005 Member, Tourette Syndrome Association Scientific Advisory Board

Regional
1995-2001 Member, Institutional Review Board     National Institute of Mental Health

Memberships, Offices, and Committee Assignments in Professional Societies
1987 American Academy of Child and Adolescent Psychiatry
1998-2003 American College of Neuropsychopharmacology (ACNP), Associate Member
1998 American Society of Hispanic Psychiatry
1992 Society for Biological Psychiatry
1994 Society for Neuroscience
2003 Member, ACNP
2003-2006 Member, Ethics Committee, ACNP
2008-2011 Member, Program Committee, American Academy of Child and Adolescent Psychiatry
2010-2012 Member, Education and Training Committee, ACNP

Editorial Boards
2002 - 2010 Journal of Child & Adolescent Psychopharmacology
2005 - Journal of Child Psychology and Psychiatry
2005 - 2011  Journal of the American Academy of Child and Adolescent Psychiatry
2008 - Journal of Attention Disorders
2010 - Brain Connectivity, Founding member
Action Editor  (Surrogate Editor for editorial conflicts of interest)
2008 - 2011 Journal of the American Academy of Child and Adolescent Psychiatry

Ad Hoc Reviewer
American Journal of Medical Genetics; American Journal of Psychiatry; Annals of Neurology; Archives of General Psychiatry; Behavioral Brain Functions; Biological Psychiatry; BMC Psychiatry; Brain; Brain Research; Cerebral Cortex; Child Neuropsychology; Clinical Neurophysiology; Clinical Neuropharmacology; Developmental Medicine and Child Neurology; European Child and Adolescent Psychiatry; European Journal of Neuroscience; Human Brain Mapping; Journal of Abnormal Psychology; Journal of Attention Disorders; Journal of Abnormal Psychology; Journal of Clinical and Experimental Neuropsychology; Journal of Clinical Psychopharmacology; Journal of Cognitive Neuroscience; Journal of Developmental and Behavioral Pediatrics; Journal of Psychiatry & Neuroscience; Journal of Neuroscience; JAMA; Molecular Psychiatry; NeuroImage; Neuropsychologia; Neuropsychopharmacology; Neuroscience Letters; Neuroscience and Biobehavioral Reviews; Pediatrics; Physiology & Behavior; PLoS Computational Biology; Psychological Bulletin; Psychological Medicine; Psychiatry Research: Neuroimaging; Neuropsychopharmacology; Proceedings of the National Academy of Sciences; Psychopharmacology.

Principal Clinical and Hospital Service Responsibilities
1991 - 2001 Attending Physician, Child Psychiatry Branch Clinical Center of the NIH

Major Administrative Responsibilities
2003 - 2010 Director of Research, NYU Child Study Center
2006 -  Director of Child and Adolescent Psychiatry Research, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY
2010 -  Vice-Chair for Research, Department of Child and Adolescent Psychiatry and NYU Child Study Center, NYU Langone Medical Center School of Medicine

Teaching Experience
2002 - 2004 Research Methods Course Director and Lecturer 1 ½ hours per week
2006 - 2008 Ethical Conduct of Research - 3 hourly sessions as part of Psychiatry PGY2 didactics
2008 -  Guest lecturer on Neuroscience of ADHD in NYU Neuroscience Consortium graduate course on CNS Disorders and Neuroscience

Teaching Awards Received
2004 Teacher of the Year Award presented by the 2004 graduating class of Child and Adolescent Psychiatry Residents.

Major Research Interests

  1. Anatomic and functional neuroimaging of childhood onset psychiatric disorders, with emphasis on attention-deficit/hyperactivity  disorder (ADHD) and autism spectrum disorders
  2. Genetics of ADHD and disruptive behavior disorders
  3. Psychopharmacology of ADHD and Tourette disorder
  4. Translational developmental neuroscience of ADHD, autism, anxiety and related disorders, including substance abuse disorders

Grants Received
Agency Title Type & # Period Total Direct Costs Role %Effort
XXXXXXXXXXXXXX
XXXXXXXXXX		 Optical Imaging of
Pediatric Neuropsychiatric
Disorders		 Foundation

11/01 – 08/04

 $XXXXXXX PI

XX%
National Institute of 
Mental Health		 Cerebellar-Striatal-
Prefrontal Dysfunction
in ADHD		 R21
MH66393

9/12/02 – 8/31/07

 $525,000 PI

25%
 National Institute of
Mental Health		 Research Training in
Child and Adolescent
Mental Health		 T32
MH67763

7/1/03 – 6/30-09

 $1,269,864 PI

20%
National Institute on
Drug Abuse		 Childhood Stimulant
Exposure Impact on
Later Drug Abuse		 R01 DA
016979-01

9/30/03 – 6/30/10*

 $1,620,097 PI

15%
XXXXXX Deficient Modulation of
Physiological Fluctuations
In Attention		 Distinguished
Investigator's
Award

5/1/05 – 4/31/07

 $XXXXXXX PI

XX%
National Institute of
Mental Health		 Neurocognitive Mechanisms
of Pediatric Anxiety
Disorders		 K23MH
074821

8/1/05 – 7/31/10

 $720,000 Mentor

5% (no
salary)
National Institute of
Mental Health		 The Neurobiology of
Adolescent Depression		 K23MH
077072-01A1

2/1/07 – 1/31/12

 $839,500 Mentor

5% (no
salary)
National Institute on
Drug Abuse		 Functional and Structural
Connectivity in Cocaine
Addiction		 R03DA
024775-01

5/15/08 – 4/30/10*

 $155,411 Co-I;
Mentor

1%
National Institute of
Mental Health		 Neural Substrates of
Variability in Attention-Deficit/Hyperactivity
Disorder (ADHD) 		R01MH
081218-01A1

4/1/08 – 5/31/11

 $1,105,735 PI

15%
XXXXXXXXXXXXXX
XXXXXXXXXX		 High-Throughput
Neuroimaging of Pediatric
Neuropsychiatric Disorders		 Foundation
1:1 Matching
Grant

5/1/08 – 4/30/11

 $XXXXXXX PI XXX
XXXXXXXXXXXXX
XXXXXXXXXXX		 Functional Connectivity
in Tourette Syndrome:
A Pilot Study		 Foundation

7/1/08 – 6/30/10

 $XXXXXXX PI XXX
XXXXXXXXXXX Early Development of
Brain Connectivity in
Autism		 High Impact
High Risk
Program

1/1/09 – 12/31/11

 $XXXXXXX PI XXX
National Institute of
Mental Health		 Functional and Structural
Connectivity in Adult
Attention-Deficit/
Hyperactivity Disorder
(ADHD) 		R01MH
083246-01A1

2/15/09 – 12/30/11

 $1,156,085 PI

15%
National Institute of
Mental Health		 Research Training in
Translational
Developmental
Neuroscience 		NRSA T32
MH67763-06

7/1/09 – 6/30/14

 $1,542,046;
Supports 5 post-
doctoral and 2 pre-
doctoral stipends/yr 		PI

20% (no
salary)
National Institute of 
Mental Health		 Connectivity of the
Anterior Cingulate Cortex
Network in Autism		 R21MH
084126-01A1

4/1/09 – 3/31/11

 $275,000 Co-I;
Mentor

2.5%
National Institute of
Biomedical Imaging
and Bioengineering		 Quantitative MRI of
Microstructure and Iron
Homeostasis in ADHD
Brain		 R01EB
007656-01A2

9/1/09 – 8/31/10

 $600,000 Co-I

10%
National Institute of 
Mental Health		 Development of Cortical-
Amygdala Interactions		 R21MH
086952-01

7/1/09 – 6/30/12

 $600,000 PI

10%
National Center for
Research Resources		 Institutional Clinical and
Translational Science
Award		 1UL1RR
029893-01

7/14/09 – 3/31/14

 $5,480,123 Co-I

10%
National Institute of
Child Health & Human
Development		 Neural Dissection of
Hyperactivity/Inattention
In Autism		 R01HD065282

10/1/09 – 9/30/11

 $1,396,142 PI

15%
National Institute of
Mental Health 		Translational
Developmental
Neuroscience of Autism		 K23MH
087770-01-A1

1/1/10 – 12/31/13

 $600,000 Co-I;
Mentor

5% (no
salary)
    NCE = no cost extension

Pending Grants
Agency Title Type & # Period Total Direct Costs Role %Effort
             

Patents

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX
XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX

Boards and Community Organizations

None

Military Service

None

Other

None

 

Bibliography

Peer Reviewed Publications

  1. Helpern JA, Adisetiyo V, Falangola MF, Hu C, Di MA, Williams K, Castellanos FX, Jensen JH. Preliminary evidence of altered gray and white matter microstructural development in the frontal lobe of adolescents with attention-deficit hyperactivity disorder: A diffusional kurtosis imaging study.  J Magn Reson Imaging 33:17-23, 2011.
  2. Arcos-Burgos M, Jain M, Acosta MT, Shively S, Stanescu H, Wallis D, Domené S, Vélez JI, Karkera JD, Balog J, Berg K, Kleta R, Gahl WA, Roessler E, Long R, Lie J, Pineda D, Londoño AC, Palacio JD, Arbelaez A, Lopera F, Elia J, Hakonarson H, Johansson S, Knappskog PM, Haavik J, Ribases M, Cormand B, Bayes M, Casas M, Ramos T, Hervas A, Maher BS, Seitz C, Freitag CM, Palmason H, Meyer J, Romanos M, Walitza S, Hemminger U, Warnke A, Romanos J, Renner T, Jacob C, Lesch KP, Faraone SV, Swanson J, Vortmeyer A, Bailey-Wilson JE, Castellanos FX, Muenke M. A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication.  Mol Psychiatry in press2010.
  3. Biswal BB, Mennes M, Zuo XN, Gohel S, Kelly C, Smith SM, Beckmann CF, Adelstein JS, Buckner RL, Colcombe SJ, Dogonowski AM, Ernst M, Fair DA, Hampson M, Hoptman MJ, Hyde JS, Kiviniemi VJ, Kötter R, Li SJ, Lin CP, Lowe MJ, Mackay C, Madden DJ, Madsen KH, Margulies DS, Mayberg HS, McMahon K, Monk CS, Mostofsky SH, Nagel BJ, Pekar JJ, Peltier SJ, Petersen SE, Riedl V, Rombouts SARB, Rypma B, Schlaggar BL, Schmidt S, Seidler RD, Siegle GJ, Sorg C, Teng GJ, Veijola J, Villringer A, Walter M, Wang L, Weng XC, Whitfield-Gabrieli S, Williamson P, Windischberger C, Zang YF, Zhang HY, Castellanos FX, Milham MP. Toward discovery science of human brain function.  Proc Natl Acad Sci U S A 107:4734-4739, 2010.
  4. Cox CL, Gotimer K, Roy AK, Castellanos FX, Milham MP, Kelly C. Your resting brain CAREs about your risky behavior.  PLoS ONE 5:e122962010.
  5. Di Martino A, Kelly C, Grzadzinski R, Zuo XN, Mennes M, Mairena MA, Lord C, Castellanos FX, Milham MP. Aberrant striatal functional connectivity in children with autism.  Biol Psychiatry in press2010.
  6. Dickstein DP, Gorrostieta C, Ombao H, Goldberg LD, Brazel AC, Gable CJ, Kelly C, Gee DG, Zuo XN, Castellanos FX, Milham MP. Fronto-temporal spontaneous resting state functional connectivity in pediatric bipolar disorder.  Biol Psychiatry 2010.
  7. Gee DG, Biswal BB, Kelly C, Stark DE, Margulies DS, Shehzad Z, Uddin LQ, Klein DF, Banich MT, Castellanos FX, Milham MP. Low frequency fluctuations reveal integrated and segregated processing among the cerebral hemispheres.  Neuroimage 2010.
  8. Gomez-Guerrero L, Dominguez MC, Mairena MA, Di MA, Wang J, Mendelsohn AL, Dreyer BP, Isquith PK, Gioia G, Petkova E, Castellanos FX. Response time variability is related to parent ratings of inattention, hyperactivity, and executive function.  J Atten Disord 2010.
  9. Grzadzinski R, Di MA, Brady E, Mairena MA, O'Neale M, Petkova E, Lord C, Castellanos FX. Examining autistic traits in children with ADHD: does the autism spectrum extend to ADHD?  J Autism Dev Disord 2010.
  10. Hoptman MJ, D'Angelo D, Catalano D, Mauro CJ, Shehzad ZE, Kelly AMC, Castellanos FX, Javitt DC, Milham MP. Amygdalofrontal functional disconnectivity and aggression in schizophrenia.  Schizophr Bull 36:1020-1028, 2010.
  11. Kelly C, Uddin LQ, Shehzad Z, Margulies DS, Castellanos FX, Milham MP, Petrides M. Broca's region: linking human brain functional connectivity data and non-human primate tracing anatomy studies.  Eur J Neurosci 32:383-398, 2010.
  12. Kieling C, Kieling RR, Rohde LA, Frick PJ, Moffitt T, Nigg JT, Tannock R, Castellanos FX. The age of onset of attention deficit hyperactivity disorder.  Am J Psychiatry 167:1-3, 2010.
  13. Koyama MS, Kelly C, Shehzad Z, Penesetti D, Castellanos FX, Milham MP. Reading networks at rest.  Cereb Cortex In press2010.
  14. Linares LO, Li M, Shrout PE, Ramirez-Gaite M, Hope S, Albert A, Castellanos FX. The course of inattention and hyperactivity/impulsivity symptoms after foster placement.  Pediatrics 2010.
  15. Mannuzza S, Castellanos FX, Roizen ER, Hutchison JA, Lashua EC, Klein RG. Impact of the impairment criterion in the diagnosis of adult ADHD: 33-year follow-up study of boys with ADHD.  J Atten Disord 2010.
  16. Mennes M, Kelly C, Zuo XN, Di Martino A, Biswal B, Castellanos FX, Milham MP. Inter-individual differences in resting state functional connectivity predict task-induced BOLD activity.  Neuroimage 50:1690-1701, 2010a.
  17. Mennes M, Zuo XN, Kelly C, Di Martino A, Zang YF, Biswal B, Castellanos FX, Milham MP. Linking inter-individual differences in neural activation and behavior to intrinsic brain dynamics.  Neuroimage in press2010b.
  18. Ribases M, Ramos-Quiroga JA, Sanchez-Mora C, Bosch R, Richarte V, Alvarez I, Gastaminza X, Bielsa A, Arcos-Burgos M, Muenke M, Castellanos FX, Cormand B, Bayes M, Casas M. Contribution of Latrophilin 3 (LPHN3) to the genetic susceptibility to ADHD in adulthood: a replication study.  Genes Brain Behav in press2010.
  19. Zuo XN, Di Martino A, Kelly C, Shehzad ZE, Gee DG, Klein DF, Castellanos FX, Biswal BB, Milham MP. The oscillating brain: complex and reliable.  Neuroimage 49:1432-1445, 2010a.
  20. Zuo XN, Kelly C, Adelstein JS, Klein DF, Castellanos FX, Milham MP. Reliable intrinsic connectivity networks: test-restest evaluation using ICA and dual regression approach.  Neuroimage 49:2163-2177, 2010b.
  21. Zuo XN, Kelly C, Di Martino A, Mennes M, Margulies DS, Bangaru S, Grzadzinski R, Evans A, Zang Y, Castellanos FX, Milham MP. Growing together and growing apart: Regional and sex differences in the lifespan developmental trajectories of functional homotopy.  J Neurosci 30:15034-15043, 2010c.
  22. Cullen KR, Gee DG, Klimes-Dougan B, Gabbay V, Hulvershorn L, Mueller BA, Camchong J, Bell CJ, Houri A, Kumra S, Lim KO, Castellanos FX, Milham MP. A preliminary study of functional connectivity in comorbid adolescent depression.  Neurosci Lett 460:227-231, 2009.
  23. Di Martino A, Ross K, Uddin LQ, Sklar AB, Castellanos FX, Milham MP. Functional brain correlates of social and non-social processes in autism spectrum disorders: an ALE meta-analysis.  Biol Psychiatry 65:63-74, 2009a.
  24. Di Martino A, Shehzad Z, Kelly AMC, Roy AK, Gee DG, Uddin LQ, Gotimer K, Klein DF, Castellanos FX, Milham MP. Autistic traits in neurotypical adults are related to cingulo-insular functional connectivity.  Am J Psychiatry 166:891-899, 2009b.
  25. Hoptman MJ, D'Angelo D, Catalano D, Mauro CJ, Shehzad ZE, Kelly AMC, Castellanos FX, Javitt DC, Milham MP. Amygdalofrontal functional disconnectivity and aggression in schizophrenia.  Schizophr Bull 2009.
  26. Kelly AMC, Di Martino A, Uddin LQ, Shehzad Z, Gee DG, Reiss PT, Margulies DS, Castellanos FX, Milham MP. Development of anterior cingulate functional connectivity from late childhood to early adulthood.  Cereb Cortex 19:640-657, 2009a.
  27. Kelly AMC, de Zubicaray GI, Di Martino A, Copland DA, Reiss PT, Klein DF, Castellanos FX, Milham MP, McMahon K. L-dopa modulates functional connectivity in striatal cognitive and motor networks: a double-blind placebo-controlled study.  J Neurosci 29:7364-7378, 2009b.
  28. Margulies DS, Vincent JL, Kelly C, Lohmann G, Uddin LQ, Biswal BB, Villringer A, Castellanos FX, Milham MP, Petrides M. Precuneus shares intrinsic functional architecture in humans and monkeys.  Proc Natl Acad Sci U S A 106:20069-20074, 2009.
  29. Roy AK, Shehzad Z, Margulies DS, Kelly AMC, Uddin LQ, Gotimer K, Biswal BB, Castellanos FX, Milham MP. Functional connectivity of the human amygdala using resting state fMRI.  Neuroimage 45:614-626, 2009.
  30. Shehzad Z, Kelly AM, Reiss PT, Gee DG, Gotimer K, Uddin LQ, Lee SH, Margulies DS, Roy AK, Biswal BB, Petkova E, Castellanos FX, Milham MP. The resting brain: unconstrained yet reliable.  Cereb Cortex 19:2209-2229, 2009.
  31. Uddin LQ, Kelly AMC, Biswal BB, Castellanos FX, Milham MP. Functional connectivity of default mode network components: correlation, anticorrelation, and causality.  Hum Brain Mapp 30:625-637, 2009.
  32. Wallis D, Arcos-Burgos M, Jain M, Castellanos FX, Palacio JD, Pineda D, Lopera F, Stanescu H, Pineda D, Berg K, Palacio LG, Bailey-Wilson JE, Muenke M. Polymorphisms in the neural nicotinic acetylcholine receptor a4 subunit (CHRNA4) are associated with ADHD in a genetic isolate.  ADHD Attention Deficit and Hyperactivity Disorders 1:19-24, 2009.
  33. Acosta MT, Castellanos FX, Bolton KL, Balog JZ, Eagen P, Nee L, Jones J, Palacio L, Sarampote C, Russell HF, Berg K, Arcos-Burgos M, Muenke M. Latent class subtyping of attention-deficit/hyperactivity disorder and comorbid conditions.  J Am Acad Child Adolesc Psychiatry 47:797-807, 2008.
  34. Castellanos FX, Margulies DS, Kelly AMC, Uddin LQ, Ghaffari M, Kirsch A, Shaw D, Shehzad Z, Di Martino A, Biswal B, Sonuga-Barke EJS, Rotrosen J, Adler LA, Milham MP. Cingulate-precuneus interactions: a new locus of dysfunction in adult attention-deficit/hyperactivity disorder.  Biol Psychiatry 63:332-337, 2008.
  35. Di Martino A, Ghaffari M, Curchack J, Reiss P, Hyde C, Vannucci M, Petkova E, Klein DF, Castellanos FX. Decomposing intra-subject variability in children with attention-deficit/hyperactivity disorder.  Biol Psychiatry 64:607-614, 2008a.
  36. Di Martino A, Scheres A, Margulies DS, Kelly AMC, Uddin LQ, Shehzad Z, Biswal B, Walters JR, Castellanos FX, Milham MP. Functional connectivity of human striatum: a resting state fMRI study.  Cereb Cortex 18:2735-2747, 2008b.
  37. Dockstader C, Gaetz W, Cheyne D, Wang F, Castellanos FX, Tannock R. MEG event-related desynchronization and synchronization deficits during basic somatosensory processing in individuals with ADHD.  Behav Brain Funct 4:8-[Open Access],2008.
  38. Falangola MF, Jensen JH, Babb JS, Hu C, Castellanos FX, Di Martino A, Ferris SH, Helpern JA. Age-related non-Gaussian diffusion patterns in the prefrontal brain.  J Magn Reson Imaging 28:1345-1350, 2008.
  39. Foley M, McClowry SG, Castellanos FX. The relationship between attention deficit hyperactivity disorder and child temperament.  Journal of Applied Developmental Psychology 29:157-169, 2008.
  40. Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP. Competition between functional brain networks mediates behavioral variability.  Neuroimage 39:527-537, 2008.
  41. Krain AL, Gotimer K, Hefton S, Ernst M, Castellanos FX, Pine DS, Milham MP. An fMRI investigation of uncertainty in adolescents with anxiety disorders.  Biol Psychiatry 63:563-568, 2008.
  42. Mannuzza S, Klein RG, Truong NL, Moulton JL, III, Roizen ER, Howell KH, Castellanos FX. Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood.  Am J Psychiatry 165:604-609, 2008.
  43. Stark DE, Margulies DS, Shehzad Z, Reiss P, Kelly AMC, Uddin LQ, Gee DG, Roy AK, Banich MT, Castellanos FX, Milham MP. Regional variation in interhemispheric coordination of intrinsic hemodynamic fluctuations.  J Neurosci 28:13754-13764, 2008.
  44. Uddin LQ, Kelly AMC, Biswal BB, Margulies DS, Shehzad Z, Shaw D, Ghaffari M, Rotrosen J, Adler LA, Castellanos FX, Milham MP. Network homogeneity reveals decreased integrity of default-mode network in ADHD.  J Neurosci Methods 169:249-254, 2008a.
  45. Uddin LQ, Mooshagian E, Zaidel E, Scheres A, Margulies DS, Kelly AMC, Shehzad Z, Adelstein JS, Castellanos FX, Biswal BB, Milham MP. Residual functional connectivity in the split-brain revealed with resting-state fMRI.  NeuroReport 19:703-709, 2008b.
  46. Zhou K, Dempfle A, Arcos-Burgos M, Bakker SC, Banaschewski T, Biederman J, Buitelaar J, Castellanos FX, Doyle A, Ebstein RP, Ekholm J, Forabosco P, Franke B, Freitag C, Friedel S, Gill M, Hebebrand J, Hinney A, Jacob C, Lesch KP, Loo SK, Lopera F, McCracken JT, McGough JJ, Meyer J, Mick E, Miranda A, Muenke M, Mulas F, Nelson SF, Nguyen TT, Oades RD, Ogdie MN, Palacio JD, Pineda D, Reif A, Renner TJ, Roeyers H, Romanos M, Rothenberger A, Schafer H, Sergeant J, Sinke RJ, Smalley SL, Sonuga-Barke E, Steinhausen HC, van der Meulen E, Walitza S, Warnke A, Lewis CM, Faraone SV, Asherson P. Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder.  Am J Med Genet B Neuropsychiatr Genet 147B:1392-1398, 2008.
  47. Durston S, Davidson MC, Mulder MJ, Spicer JA, Galvan A, Tottenham N, Scheres A, Castellanos FX, van Engeland H, Casey BJ. Neural and behavioral correlates of expectancy violations in attention-deficit hyperactivity disorder.  J Child Psychol Psychiatry 48:881-889, 2007.
  48. Gornick MC, Addington A, Shaw P, Bobb AJ, Sharp W, Greenstein D, Arepalli S, Castellanos FX, Rapoport JL. Association of the dopamine receptor D4 (DRD4) gene 7-repeat allele with children with attention-deficit/hyperactivity disorder (ADHD): An update.  Am J Med Genet B Neuropsychiatr Genet 144B:379-382, 2007.
  49. Heijtz RD, Alexeyenko A, Castellanos FX. Calcyon mRNA expression in the frontal-striatal circuitry and its relationship to vesicular processes and ADHD.  Behav Brain Funct July 10:3-33, 2007.
  50. Jain M, Palacio LG, Castellanos FX, Palacio JD, Pineda D, Restrepo MI, Munoz JF, Lopera F, Wallis D, Berg K, Bailey-Wilson JE, Arcos-Burgos M, Muenke M. Attention-deficit/hyperactivity disorder and comorbid disruptive behavior disorders: evidence of pleiotropy and new susceptibility loci.  Biol Psychiatry 61:1329-1339, 2007.
  51. Margulies DS, Kelly AMC, Uddin LQ, Biswal BB, Castellanos FX, Milham MP. Mapping the functional connectivity of anterior cingulate cortex.  Neuroimage 37:579-588, 2007.
  52. Scheres A, Milham MP, Knutson B, Castellanos FX. Ventral striatal hyporesponsiveness during reward anticipation in attention-deficit/hyperactivity disorder.  Biol Psychiatry 61:720-724, 2007.
  53. Shaw P, Gornick M, Lerch J, Addington A, Seal J, Greenstein D, Sharp W, Evans A, Giedd J, Castellanos FX, Rapoport JL. Polymorphisms of the dopamine D4 receptor, clinical outcome and cortical structure in attention-deficit/hyperactivity disorder.  Arch Gen Psychiatry 64:921-931, 2007.
  54. Diaz Heijtz R, Castellanos FX. Differential effects of a selective dopamine D1-like receptor agonist on motor activity and c-fos expression in the frontal-striatal circuitry of SHR and Wistar-Kyoto rats.  Behav Brain Funct 2:182006.
  55. Dickstein SG, Bannon K, Castellanos FX, Milham MP. The neural correlates of attention deficit hyperactivity disorder: an ALE meta-analysis.  J Child Psychol Psychiatry 47:1051-1062, 2006.
  56. Glaser PEA, Surgener SP, Grondin R, Gash CR, Palmer M, Castellanos FX, Gerhardt GA. Cerebellar neurotransmission in attention-deficit/hyperactivity disorder: does dopamine neurotransmission occur in the cerebellar vermis?  J Neurosci Methods 15:62-67, 2006.
  57. Krain AL, Wilson AM, Arbuckle R, Castellanos FX, Milham MP. Distinct neural mechanisms of risk and ambiguity: a meta-analysis of decision-making.  Neuroimage 32:477-484, 2006a.
  58. Krain AL, Hefton S, Pine DS, Ernst M, Castellanos FX, Klein RG, Milham MP. An fMRI examination of developmental differences in the neural correlates of uncertainty and decision-making.  J Child Psychol Psychiatry 47:1023-1030, 2006b.
  59. Mulas F, Capilla A, Fernandez S, Etchepareborda MC, Campo P, Maestu F, Fernandez A, Castellanos FX, Ortiz T. Shifting-related brain magnetic activity in attention-deficit/hyperactivity disorder.  Biol Psychiatry 59:373-379, 2006.
  60. Scheres A, Dijkstra M, Ainslie E, Balkan J, Reynolds B, Sonuga-Barke E, Castellanos FX. Temporal and probabilistic discounting of rewards in children and adolescents: effects of age and ADHD symptoms.  Neuropsychologia 44:2092-2103, 2006.
  61. Shaw P, Lerch J, Greenstein D, Sharp W, Clasen L, Evans A, Giedd J, Castellanos FX, Rapoport J. Longitudinal mapping of cortical thickness and clinical outcome in children and adolescents with attention-deficit/hyperactivity disorder.  Arch Gen Psychiatry 63:540-549, 2006.
  62. Bobb AJ, Addington AM, Sidransky E, Gornick MC, Lerch JP, Greenstein DK, Clasen LS, Sharp WS, Inoff-Germain G, Wavrant-De Vrieze F, Arcos-Burgos M, Straub RE, Hardy JA, Castellanos FX, Rapoport JL. Support for association between ADHD and two candidate genes: NET1 and DRD1.  Am J Med Genet B Neuropsychiatr Genet 134:67-72, 2005.
  63. Castellanos FX, Sonuga-Barke EJS, Scheres A, Di Martino A, Hyde C, Walters JR. Varieties of attention-deficit/hyperactivity disorder-related intra-individual variability.  Biol Psychiatry 57:1416-1423, 2005.
  64. Dickstein DP, Garvey M, Pradella A, Greenstein D, Sharp W, Castellanos FX, Pine D, Leibenluft E. Neurologic examination abnormalities in children with bipolar disorder or attention-deficit/hyperactivity disorder.  Biol Psychiatry 58:517-524, 2005.
  65. Garvey MA, Barker CA, Bartko JJ, Denckla MB, Wassermann EM, Castellanos FX, Dell ML, Ziemann U. The ipsilateral silent period in boys with attention-deficit/hyperactivity disorder.  Clin Neurophysiol 116:1889-1896, 2005.
  66. Glaser PE, Thomas TC, Joyce BM, Castellanos FX, Gerhardt GA. Differential effects of amphetamine isomers on dopamine release in the rat striatum and nucleus accumbens core.  Psychopharmacology 178:250-258, 2005.
  67. Nicolson R, Craven-Thuss B, Smith J, McKinlay BD, Castellanos FX. A randomized, double-blind, placebo-controlled trial of metoclopramide for the treatment of Tourette's disorder.  J Am Acad Child Adolesc Psychiatry 44:640-646, 2005.
  68. Acosta MT, Castellanos FX. Use of the "inverse neuroleptic" metoclopramide in Tourette syndrome: an open case series.  J Child Adolesc Psychopharmacol 14:123-128, 2004.
  69. Arcos-Burgos M, Castellanos FX, Pineda D, Lopera F, David PJ, Guillermo PL, Rapoport JL, Berg K, Bailey-Wilson JE, Muenke M. Attention-deficit/hyperactivity disorder in a population isolate: linkage to Loci at 4q13.2, 5q33.3, 11q22, and 17p11.  Am J Hum Genet 75:998-1014, 2004a.
  70. Arcos-Burgos M, Castellanos FX, Konecki D, Lopera F, Pineda D, Palacio JD, Rapoport JL, Berg K, Bailey-Wilson J, Muenke M. Pedigree disequilibrium test (PDT) replicates association and linkage between DRD4 and ADHD in multigenerational and extended pedigrees from a genetic isolate.  Mol Psychiatry 9:252-259, 2004b.
  71. Palacio JD, Castellanos FX, Pineda DA, Lopera F, Arcos-Burgos M, Quiroz YT, Henao GC, Puerta IC, Ramirez DL, Rapoport JL, Bailey-Wilson J, Berg K, Muenke M. Attention-deficit/hyperactivity disorder and comorbidities in 18 Paisa Colombian multigenerational families.  J Am Acad Child Adolesc Psychiatry 46:1506-1515, 2004.
  72. Reinblatt SP, Rifkin A, Castellanos FX, Coffey BJ. General psychiatry residents' perceptions of specialized training in the field of mental retardation.  Psychiatr Serv 55:312-314, 2004.
  73. Castellanos FX, Sharp WS, Gottesman RF, Greenstein DK, Giedd JN, Rapoport JL. Anatomic brain abnormalities in monozygotic twins discordant for attention deficit hyperactivity disorder.  Am J Psychiatry 160:1693-1696, 2003.
  74. Keller A, Castellanos FX, Vaituzis AC, Jeffries NO, Giedd JN, Rapoport JL. Progressive loss of cerebellar volume in childhood-onset schizophrenia.  Am J Psychiatry 160:128-133, 2003.
  75. Sharp WS, Gottesman RF, Greenstein DK, Ebens CL, Rapoport JL, Castellanos FX. Monozygotic twins discordant for attention-deficit/hyperactivity disorder: ascertainment and clinical characteristics.  J Am Acad Child Adolesc Psychiatry 42:93-97, 2003.
  76. Arcos-Burgos M, Castellanos FX, Lopera F, Pineda D, Palacio JD, Garcia M, Henao GC, Palacio LG, Berg K, Bailey-Wilson JE, Muenke M. Attention-deficit/hyperactivity disorder (ADHD): Feasibility of linkage analysis in a genetic isolate using extended and multigenerational pedigrees.  Clin Genet 61:335-343, 2002.
  77. Bastain TM, Lewczyk CM, Sharp WS, James RS, Long RT, Eagen PB, Ebens CL, Meck JM, Chan WY, Sidransky E, Rapoport JL, Castellanos FX. Cytogenetic abnormalities in attention-deficit/hyperactivity disorder.  J Am Acad Child Adolesc Psychiatry 41:806-810, 2002.
  78. Castellanos FX, Lee PP, Sharp W, Jeffries NO, Greenstein DK, Clasen LS, Blumenthal JD, James RS, Ebens CL, Walter JM, Zijdenbos A, Evans AC, Giedd JN, Rapoport JL. Developmental trajectories of brain volume abnormalities in children and adolescents with attention-deficit/hyperactivity disorder.  JAMA 288:1740-1748, 2002.
  79. Asherson P, Barr C, Biederman J, Buitelaar J, Castellanos X, Curran S, Doyle A, Ebstein R, Eisenberg J, Faraone SV, Gill M, Hay D, Holmes J, Hudziak J, Kennedy J, Kent L, Levy F, Manor I, Mick E, Price T, Rohde LA, Rowe D, Sargeant J, Simonoff E, Spencer T, Swanson J, Taylor E, Todd R, Waldman I, Yazgan Y. Report from the Second International Meeting of the Attention Deficit Hyperactivity Disorder Molecular Genetics Network.  Am J Med Genet 105:255-258, 2001.
  80. Castellanos FX, Giedd JN, Berquin PC, Walter JM, Sharp W, Tran T, Vaituzis AC, Blumenthal J, Nelson J, Bastain TM, Zijdenbos A, Evans AC, Rapoport JL. Quantitative brain magnetic resonance imaging in girls with attention-deficit/hyperactivity disorder.  Arch Gen Psychiatry 58:289-295, 2001.
  81. Gould TD, Bastain TM, Israel ME, Hommer DW, Castellanos FX. Altered performance on an ocular fixation task in attention-deficit/hyperactivity disorder.  Biol Psychiatry 50:633-635, 2001.
  82. James RS, Sharp WS, Bastain TM, Lee PP, Walter JM, Czarnolewski M, Castellanos FX. A double-blind placebo-controlled study of single-dose amphetamine formulations in ADHD.  J Am Acad Child Adolesc Psychiatry 40:1268-1276, 2001.
  83. Castellanos FX, Marvasti FF, Ducharme JL, Walter JM, Israel ME, Krain AL, Pavlovsky C, Hommer DW. Executive function oculomotor tasks in girls with ADHD.  J Am Acad Child Adolesc Psychiatry 39:644-650, 2000.
  84. Nopoulos P, Berg S, Castellanos FX, Delgado A, Andreasen NC, Rapoport JL. Developmental brain anomalies in children with attention deficit hyperactivity disorder.  J Child Neurol 15:102-108, 2000.
  85. Castellanos FX, Lau E, Tayebi N, Lee P, Long RE, Giedd JN, Sharp WS, Marsh WL, Walter JM, Hamburger SD, Ginns EI, Rapoport JL, Sidransky E. Sampling and analytic considerations in molecular genetics studies of ADHD. The advantages of predicting phenotype from genotype in ADHD research - Castellanos replies.  Mol Psychiatry 4:4141999.
  86. Giedd JN, Blumenthal J, Jeffries NO, Rajapakse JC, Vaituzis AC, Liu H, Berry YC, Tobin M, Nelson J, Castellanos FX. Development of the human corpus callosum during childhood and adolescence: a longitudinal MRI study.  Prog Neuropsychopharmacol Biol Psychiatry 23:571-588, 1999a.
  87. Giedd JN, Blumenthal J, Jeffries NO, Castellanos FX, Liu H, Zijdenbos A, Paus T, Evans AC, Rapoport JL. Brain development during childhood and adolescence: a longitudinal MRI study.  Nat Neurosci 2:861-863, 1999b.
  88. Giedd JN, Jeffries NO, Blumenthal J, Castellanos FX, Vaituzis AC, Fernandez T, Hamburger SD, Liu H, Nelson J, Bedwell J, Tran L, Lenane M, Nicolson R, Rapoport JL. Childhood-onset schizophrenia: progressive brain changes during adolescence.  Biol Psychiatry 46:892-898, 1999c.
  89. Sharp WS, Walter JM, Marsh WL, Ritchie GF, Hamburger SD, Castellanos FX. ADHD in girls: Clinical comparability of a research sample.  J Am Acad Child Adolesc Psychiatry 38:40-47, 1999.
  90. Berquin PC, Giedd JN, Jacobsen LK, Hamburger SD, Krain AL, Rapoport JL, Castellanos FX. The cerebellum in attention-deficit/hyperactivity disorder: a morphometric study.  Neurology 50:1087-1093, 1998.
  91. Castellanos FX, Lau E, Tayebi N, Lee P, Long RE, Giedd JN, Sharp WS, Marsh WL, Walter JM, Hamburger SD, Ginns EI, Rapoport JL, Sidransky E. Lack of association between a dopamine-4 receptor polymorphism and attention-deficit/hyperactivity disorder: genetic and brain morphometric analyses.  Mol Psychiatry 3:431-434, 1998.
  92. Jacobsen LK, Giedd JN, Castellanos FX, Vaituzis AC, Hamburger SD, Kumra S, Lenane M, Rapoport JL. Progressive reduction of temporal lobe structures in childhood onset schizophrenia.  Am J Psychiatry 155:678-685, 1998.
  93. Kumra S, Jacobsen LK, Lenane M, Zahn TP, Wiggs E, Alaghband-Rad J, Castellanos FX, Frazier JA, McKenna K, Gordon CT, Smith A, Hamburger SD, Rapoport JL. "Multidimensionally impaired disorder": is it a variant of very early-onset schizophrenia?  J Am Acad Child Adolesc Psychiatry 37:91-99, 1998.
  94. Perlmutter SJ, Garvey MA, Castellanos FX, Mittleman BB, Giedd JN, Rapoport JL, Swedo SE. Clinical case conference: a case of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections.  Am J Psychiatry 155:1592-1598, 1998.
  95. Casey BJ, Trainor RJ, Orendi JL, Schubert AB, Nystrom LE, Giedd JN, Castellanos FX, Haxby JV, Noll DC, Cohen JD, Forman SD, Dahl RE, Rapoport JL. A developmental functional MRI study of prefrontal activation during performance of a Go-No-Go task.  J Cogn Neurosci 9:835-847, 1997a.
  96. Casey BJ, Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Schubert AB, Vauss YC, Vaituzis AC, Dickstein DP, Sarfatti SE, Rapoport JL. Implication of right frontostriatal circuitry in response inhibition and attention-deficit/hyperactivity disorder.  J Am Acad Child Adolesc Psychiatry 36:374-383, 1997b.
  97. Castellanos FX, Giedd JN, Elia J, Marsh WL, Ritchie GF, Hamburger SD, Rapoport JL. Controlled stimulant treatment of ADHD and comorbid Tourette's syndrome: effects of stimulant and dose.  J Am Acad Child Adolesc Psychiatry 36:589-596, 1997.
  98. Giedd JN, Castellanos FX, Rajapakse JC, Vaituzis AC, Rapoport JL. Sexual dimorphism of the developing human brain.  Prog Neuropsychopharmacol Biol Psychiatry 21:1185-1201, 1997.
  99. Lange N, Giedd JN, Castellanos FX, Vaituzis AC, Rapoport JL. Variability of human brain structure size: ages 4 to 20.  Psychiatry Res Neuroimaging 74:1-12, 1997.
  100. Mittleman BB, Castellanos FX, Jacobsen LK, Rapoport JL, Swedo SE, Shearer GM. Cerebrospinal fluid cytokines in pediatric neuropsychiatric disease.  J Immunol 159:2994-2999, 1997.
  101. Castellanos FX, Elia J, Kruesi MJP, Marsh WL, Gulotta CS, Potter WZ, Ritchie GF, Hamburger SD, Rapoport JL, Kruesi MJ. Cerebrospinal homovanillic acid predicts behavioral response to stimulants in 45 boys with attention-deficit/hyperactivity disorder.  Neuropsychopharmacology 14:125-137, 1996a.
  102. Castellanos FX, Giedd JN, Hamburger SD, Marsh WL, Rapoport JL. Brain morphometry in Tourette's syndrome: the influence of comorbid attention-deficit/hyperactivity disorder.  Neurology 47:1581-1583, 1996b.
  103. Castellanos FX, Ritchie GF, Marsh WL, Rapoport JL. DSM-IV Stereotypic Movement Disorder: persistence of stereotypies of infancy in intellectually normal adolescents and adults.  J Clin Psychiatry 57:116-122, 1996c.
  104. Castellanos FX, Fine EJ, Kaysen D, Marsh WL, Rapoport JL, Hallett M. Sensorimotor gating in boys with Tourette's syndrome and ADHD: preliminary results.  Biol Psychiatry 39:33-41, 1996d.
  105. Castellanos FX, Giedd JN, Marsh WL, Hamburger SD, Vaituzis AC, Dickstein DP, Sarfatti SE, Vauss YC, Snell JW, Lange N, Kaysen D, Krain AL, Ritchie GF, Rajapakse JC, Rapoport JL. Quantitative brain magnetic resonance imaging in attention-deficit/hyperactivity disorder.  Arch Gen Psychiatry 53:607-616, 1996e.
  106. Giedd JN, Rumsey JM, Rajapakse JC, Castellanos FX, Casey BJ, Kaysen D, Vaituzis AC, Vauss YC, Hamburger SD, Rapoport JL. A quantitative MRI study of the corpus callosum in children and adolescents.  Brain Res Dev Brain Res 91:274-280, 1996.
  107. Jacobsen LK, Hommer DW, Hong WL, Castellanos FX, Frazier JA, Giedd JN, Rapoport JL. Blink rate in childhood-onset schizophrenia: comparison with normal and ADHD controls.  Biol Psychiatry 40:1222-1229, 1996a.
  108. Jacobsen LK, Hong WL, Hommer DW, Hamburger SD, Castellanos FX, Frazier JA, Giedd JN, Gordon CT, Karp BI, McKenna K, Rapoport JL. Smooth pursuit eye movements in childhood onset schizophrenia: comparison with ADHD and normal controls.  Biol Psychiatry 40:1144-1154, 1996b.
  109. Castellanos FX, Elia J, Kruesi MJP, Gulotta CS, Mefford IN, Potter WZ, Ritchie GF, Rapoport JL. Cerebrospinal fluid monoamine metabolites in boys with attention-deficit hyperactivity disorder.  Psychiatry Res 52:305-316, 1994a.
  110. Castellanos FX, Giedd JN, Eckburg P, Marsh WL, Vaituzis AC, Kaysen D, Hamburger SD, Rapoport JL. Quantitative morphology of the caudate nucleus in attention deficit hyperactivity disorder.  Am J Psychiatry 151:1791-1796, 1994b.
  111. Giedd JN, Castellanos FX, Casey BJ, Kozuch P, King AC, Hamburger SD, Rapoport JL. Quantitative morphology of the corpus callosum in attention deficit hyperactivity disorder.  Am J Psychiatry 151:665-669, 1994.
  112. Little KY, Kearfott KS, Castellanos X, Rinker A, Whitley R. Increased detection of elevated TSH using immunoradiometric assay.  Can J Psychiatry 35:342-343, 1990.
  113. Little KY, Castellanos X, Humphries LL, Austin J. Altered zinc metabolism in mood disorder patients.  Biol Psychiatry 26:646-648, 1989.
  114. Shih WJ, Humphries L, Digenis GA, Castellanos FX, Domstad PA, DeLand FH. Tc-99m labeled triethelene tetraamine polysterene resin gastric emptying studies in bulimia patients.  Eur J Nucl Med 13:192-196, 1987.
  115. Porter RJ, Jr., Castellanos FX. Speech-production measures of speech perception: rapid shadowing of VCV syllables.  J Acoust Soc Am 67:1349-1356, 1980.
  116. Castellanos FX. Naloxone effects [letter].  Neurology 29:1318-1319, 1979.
  117. King BM, Castellanos FX, Kastin AJ, Berzas MC, Mauk MD, Olson GA, Olson RD. Naloxone-induced suppression of food intake in normal and hypothalamic obese rats.  Pharmacol Biochem Behav 11:729-732, 1979.
  118. Olson GA, Olson RD, Kastin AJ, Castellanos FX, Kneale MT, Coy DH, Wolf RH. Behavioral effects of D-Ala2-beta-endorphin in squirrel monkeys.  Pharmacol Biochem Behav 9:687-691, 1978.

Chapters, Commentaries and Reviews of the Literature:

  1. Kaufmann FA, Castellanos FX. Counseling the gifted child. In: Rotatori T, Gerber P, Fox R, Litton F, editors. Counseling Exceptional Students. New York: Human Services Press, 1986: 232-251.
  2. Castellanos FX, Rapoport JL. Etiology of attention-deficit hyperactivity disorder. Child Adoles Psychiatr Clin North Am 1992; 1:373-384.
  3. Arnold LE, Stoff DM, Cook EH, Jr., Cohen DJ, Kruesi MJP, Wright C, Hattab J, Graham P, Zametkin A, Castellanos FX. Ethical issues in biological psychiatric research with children and adolescents. J Am Acad Child Adolesc Psychiatry 1995; 34:929-939.
  4. Rapoport JL, Castellanos FX. Attention-Deficit/Hyperactivity Disorder. In: Wiener JN, editor. Diagnosis and Psychopharmacology of Child and Adolescent Disorders. New York: John Wiley & Sons, Inc., 1995: 265-292.
  5. Arnold LE, Stoff DM, Cook EH, Jr., Wright C, Cohen DJ, Kruesi MJ, Hattab J, Graham P, Zametkin A, Castellanos FX, McMahon W, Leckman JF. Biologic procedures: ethical issues in research with children and adolescents. In: Hoagwood K, Jensen P, editors. Ethical issues in mental health research with children and adolescents. Mahwah, N.J.: Lawrence Erlbaum Associates, Inc., 1996: 89-111.
  6. Castellanos FX. Neurobiological disorders in children and adolescents. Decade of the Brain 1996; 7:1-2.
  7. Castellanos FX. Neuroimaging of attention-deficit hyperactivity disorder. Child Adoles Psychiatr Clin North Am 1997; 6:383-411.
  8. Castellanos FX. Toward a pathophysiology of attention-deficit/hyperactivity disorder. Clin Pediatr 1997; 36:381-393.
  9. Castellanos FX. Approaching a scientific understanding of what happens in the brain in AD/HD. Attention! 1997;30-35.
  10. Giedd JN, Castellanos FX. Developmental disorders. In: Krishnan KR, Doraiswamy PM, editors. Brain Imaging in Clinical Psychiatry. 1997: 121-143.
  11. Castellanos FX. Tic disorders and obsessive-compulsive disorder. In: Walsh BT, editor. Child Psychopharmacology. Washington D.C.: American Psychiatric Press, 1998: 1-28.
  12. Miller KJ, Castellanos FX. Management of attention-deficit/hyperactivity disorders. Pediatr Rev 1998; 19:373-384.
  13. Perlmutter SJ, Garvey MA, Castellanos FX, Mittleman BB, Giedd JN, Rapoport JL, Swedo SE. Clinical case conference: a case of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections. Am J Psychiatry 1998; 155:1592-1598.
  14. Swanson J, Castellanos FX, Murias M, LaHoste GJ, Kennedy J. Cognitive neuroscience of attention deficit hyperactivity disorder and hyperkinetic disorder. Curr Opin Neurobiol 1998; 8:263-271.
  15. Castellanos FX. The psychobiology of attention-deficit/hyperactivity disorder. In: Quay HC, Hogan AE, editors. Handbook of disruptive behavior disorders. New York: Kluwer Academic/Plenum Publishers, 1999: 179-198.
  16. Castellanos FX. Stimulants and tic disorders - From dogma to data. Arch Gen Psychiatry 1999; 56:337-338.
  17. Nicolson R, Castellanos FX. Commentary: considerations on the pharmacotherapy of attention deficits and hyperactivity in children with autism and other pervasive developmental disorders. J Autism Dev Disord 2000; 30:461-462.
  18. Paule MG, Rowland AS, Ferguson SA, Chelonis JJ, Tannock R, Swanson JM, Castellanos FX. Attention deficit/hyperactivity disorder: characteristics, interventions and models. Neurotoxicol Teratol 2000; 22:631-651.
  19. Castellanos FX. Neuroimaging studies of ADHD. In: Solanto MV, Arnsten AFT, Castellanos FX, editors. Stimulant drugs and ADHD: basic and clinical neuroscience. New York: Oxford University Press, 2001: 243-258.
  20. Castellanos FX. Neural substrates of attention-deficit/hyperactivity disorder. In: Cohen DJ, Jankovic J, Goetz CG, editors. Tourette Syndrome. Philadelphia: Lippincott Williams & Wilkins, 2001: 197-206.
  21. Giedd JN, Blumenthal J, Molloy E, Castellanos FX. Brain imaging of attention deficit/hyperactivity disorder. Ann N Y Acad Sci. 2001; 931:33-49.
  22. Solanto MV, Arnsten AFT, Castellanos FX. The neuroscience of stimulant drug action in ADHD. In: Solanto MV, Arnsten AFT, Castellanos FX, editors. Stimulant drugs and ADHD: basic and clinical neuroscience. New York: Oxford University Press, 2001: 355-379.
  23. Castellanos FX, Tannock R.  Neuroscience of attention-deficit hyperactivity disorder: the search for endophenotypes. Nat Rev Neurosci2002; 3:617-628.
  24. Castellanos FX, Rapoport JL. Effects of caffeine on development and behavior in infancy and childhood: a review of the published literature. Food Chem Toxicol, 2002; 40:1235-1242.
  25. Castellanos FX, Acosta MT. El síndrome de déficit de atención con hiperactividad como expresión de un trastorno funcional orgánico. Rev Neurol, 2002; 35:1-11.
  26. Castellanos FX. Invited commentary: Proceed, with caution:  SPECT cerebral blood flow studies of children/adolescents with attention-deficit/hyperactivity disorder.J.Nucl.Med.2002; 43:1630-1633.
  27. Castellanos FX. Anatomic magnetic resonance imaging studies of attention-deficit/hyperactivity disorder.  Dialogues Clin Neurosci 2002; 4:444-448.
  28. Arnsten AFT, Castellanos FX. Neurobiology of attention regulation and its disorders, in Martin A., Scahill L., Charney D. S., Leckman J. F., eds. Pediatric psychopharmacology. Principles and practice. New York, Oxford University Press, 2003, pp 99-109. 
  29. Brotman LM, Gouley KK, Klein RG, Castellanos FX, Pine DS. Children, stress, and context: integrating basic, clinical, and experimental prevention research.  Child Dev 2003; 74:1053-1057.  
  30. Di Martino A, Castellanos FX. Functional neuroimaging of social cognition in pervasive developmental disorders. A brief review.  Ann N Y Acad Sci 2003; 1008:256-260.   
  31. Scheres A, Castellanos FX. Review of Assessment and Treatment of Childhood Problems, 2nd Edition. A Clinicians' Guide by C.S. Schroeder and B. N. Gordon.  Psychological Medicine 2003; 33:1487-1488. 
  32. Castellanos FX, Acosta MT. [The neuroanatomy of attention deficit/hyperactivity disorder].  Rev Neurol 2004; 38 Suppl 1:131-136.  
  33. Castellanos FX, Acosta MT. [Tourette syndrome: an analysis of its comorbidity and specific treatment].  Rev Neurol 2004; 38 Suppl 1:124-130.
  34. Bobb AJ, Castellanos FX, Addington AM, Rapoport JL. Molecular genetic studies of ADHD: 1991 to 2004.  Am J Med Genet B Neuropsychiatr Genet 132:109-125, 2005.
  35. Castellanos FX, Dickstein S. A computational thought experiment based on the pharmacology of ADHD: commentary on Williams and Dayan.  J Child Adolesc Psychopharmacol 15:157-159, 2005.
  36. Seyffert M, Castellanos FX. Functional MRI in pediatric neurobehavioral disorders.  Int Rev Neurobiol 67:239-284, 2005.
  37. Castellanos FX, Sonuga-Barke EJS, Milham MP, Tannock R. Characterizing cognition in ADHD: beyond executive dysfunction.  Trends Cogn Sci 10:117-123, 2006.
  38. Castellanos FX, Glaser PE, Gerhardt GA. Towards a neuroscience of attention-deficit/hyperactivity disorder: Fractionating the phenotype.  J Neurosci Methods 151:1-4, 2006.
  39. Krain AL, Castellanos FX. Brain development and ADHD.  Clin Psychol Rev 26:433-444, 2006.
  40. Kelly AM, Margulies DS, Castellanos FX. Recent advances in structural and functional brain imaging studies of attention-deficit/hyperactivity disorder.  Curr Psychiatry Rep 9:401-407, 2007.
  41. Sonuga-Barke EJ, Castellanos FX. Spontaneous attentional fluctuations in impaired states and pathological conditions: A neurobiological hypothesis.  Neurosci Biobehav Rev 31:977-986, 2007.
  42. Swanson JM, Kinsbourne M, Nigg J, Lanphear B, Stefanatos GA, Volkow N, Taylor E, Casey BJ, Castellanos FX, Wadhwa PD. Etiologic subtypes of attention-deficit/hyperactivity disorder: brain imaging, molecular genetic and environmental factors and the dopamine hypothesis. Neuropsychol Rev 17:39-59, 2007.
  43. Kieling C, Goncalves RRF, Tannock R, Castellanos FX. Neurobiology of attention deficit hyperactivity disorder. Child Adolesc Psychiatr Clin N Am 17:285-307, 2008.
  44. Milham MP, Kelly AMC, Castellanos FX. The resting brain in ADHD: back to the future. Advances in ADHD 2:106-111, 2008.
  45. Castellanos FX. Toward the dimensionome: parsing reward-related processing in attention-deficit/hyperactivity disorder. Biol Psychiatry 65:5-6, 2009.
  46. Castellanos FX, Proal E. Location, location, and thickness: Volumetric neuroimaging of attention-deficit/hyperactivity disorder comes of age.  J Am Acad Child Adolesc Psychiatry 48:979-981, 2009.
  47. Castellanos FX, Kelly C, Milham MP. The restless brain: attention-deficit hyperactivity disorder, resting-state functional connectivity, and intrasubject variability. Can J Psychiatry 54: 665-672, 2009.
  48. Castellanos FX, Hyde Z. Diffusion tensor imaging provides new clues in adults with ADHD (Commentary on Konrad et al.) Eur J Neurosci 31: 910-911, 2010.
  49. Castellanos FX, Kelly C. Catecholamine modulators: lessons from nonhuman primates.  J Am Acad Child Adolesc Psychiatry 49:977-979, 2010.
  50. Cortese S, Castellanos FX. Dopamine reward pathway in adult ADHD.  JAMA 303:2332010.

Selected Published Proceedings:

  1. Castellanos FX, Harnett NE, Klein WE. Olfactory thresholds in boys with Tourette's syndrome and ADHD. Abstracts on New Research, 148th Annual Meeting of the American Psychiatric Association , 216. 1995.
  2. Castellanos FX, Harnett NE, Klein WE, DeMayo M. Olfaction in Tourette's syndrome ± ADHD & controls. Abstracts on New Research, 149th Annual Meeting of the American Psychiatric Association. 1996.

Monograph:

    Kaufmann FA, Kalbfleisch ML, Castellanos FX. Attention deficit disorders and gifted students: What do we really know?  2000. Storrs, CT, The National Research Center on the Gifted and Talented. Senior Scholars Series. Renzulli JS, Gubbins EJ, Callahan CM, Sternberg RJ (Eds.

Edited Book:

    Solanto MV, Arnsten AFT, Castellanos FX (Eds) Stimulant Drugs and ADHD: Basic and Clinical Neuroscience New York, Oxford University Press, 2001.

Book Translation:

    Piaget J, Grize JB, Szeminska A, Bang V: Epistemology and Psychology of Functions: Studies in Genetic Epistemology, Volume XXIII.  Translation by F. X. Castellanos and V. Anderson, Dordrecht, Netherlands: D. Reidel Publishing Co., 1977.

 

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