Curriculum Vitae: Penelope A. Fenner-Crisp

Curriculum Vitae

Penelope A. Fenner-Crisp, Ph.D., DABT

2871 Southern Hills Drive
North Garden, VA 22969-1638
Telephone: 434-244-2691
Fax: 434-296-1843
Email: pfennercrisp@aol.com

I. Personal Data

Place of Birth: XXXXXXXXXXXXXXXXXXXX
Date of Birth: XXXXXXXXXXXXXX
Marital Status: XXXXXXX
XXXXXXXXX XXXX

II. Education

Georgetown University Schools of Medicine (and Dentistry) Washington, DC.	Postdoctoral Fellowship 1971-1973
University of Texas Medical Branch Galveston, Texas	Ph.D. XXXX M.A. XXXX (Pharmacology)
University of Wisconsin-Milwaukee Milwaukee, Wisconsin	B.S. XXXX (Zoology)

III. Employment History

A. Consultant	August 2004 to present
B. Non-profit Organization
Executive Director, Risk Science Institute International Life Sciences Institute Washington, DC	December 2000-August 2004
C. Government
Senior Science Advisor to the Director, Office of Pesticide Programs U.S. Environmental Protection Agency (U.S. EPA)	Oct. 1998-Dec. 2000 (ES-04)
Special Assistant to the Assistant Administrator, Office of Prevention, Pesticides and Toxic Substances U.S. EPA	May, 1997-Oct.1998 (ES-04)
Deputy Director, Office of Pesticide Programs U.S. EPA	May, 1995-May, 1997 (ES-04)
Acting Deputy Director, Office of Pesticide Programs, U.S. EPA	May, 1994-May, 1995 (ES-04)
Director, Health Effects Division Office of Pesticide Programs U.S. EPA	May, 1989-May, 1994 (ES-03-ES-04)
Director Health and Environmental Review Division Office of Pollution Prevention and Toxic Substances U.S. EPA	Nov. 1987-May, 1989 (ES-01-ES-02)
Acting Director, Health and Environmental Review Division Office of Pollution Prevention and Toxic Substances U.S. EPA	May 1987-Nov. 1987 (GM-15)
Special Assistant to the Director Office of Pollution Prevention and Toxic Substances, U.S. EPA	Jan. 1987-May 1987 (GM-14)
Senior Toxicologist Health Effects Branch, Criteria and Standards Office of Drinking Water U.S. EPA	Oct. 1978-Dec. 1987 (GS-13, 14, Temp. GM-15)

IV. Academic

Research Associate, Department of Pharmacology Georgetown University Schools of Medicine (and Dentistry), Washington, DC.	1976-1978
Adjunct Instructor Postdoctoral Fellow Research Associate Department of Anatomy Georgetown University Schools of Medicine (and Dentistry), Washington, DC.	1971-1976
Visiting Scientist Department of Physiology University of Birmingham Medical School Birmingham, England	1974-1975
Graduate Teaching Assistant Department of Pharmacology University of Texas Medical Branch Galveston, Texas	1962-1966
Undergraduate Teaching Assistant Department of Zoology University of Wisconsin-Milwaukee Milwaukee, Wisconsin	1961-1962
Research Technician and Assistant Department of Pathology Marquette University School of Medicine Milwaukee, Wisconsin	1959, 1961-1962
Research Technician Department of Pharmacology Marquette University School of Medicine Milwaukee, Wisconsin	1959-1961

V. Professional Organizations (Partial List)

American Board of Toxicology Member of Board	1984-present 2002-2005
Society of Toxicology (Full member) Regulatory and Legislative Affairs Committee Risk Assessment Specialty Section Reproductive/Developmental Toxicology Section Carcinogenesis Specialty Section President	1983-present 1989-1991; 1998-2000 1989-present 1991-1992 1986-1996 1989
Society of Toxicology-National Capitol Area Chapter Councilor President	1986-present 1986-1988 1991-1992
Society for Risk Analysis	1981-present
Society for Risk Analysis-National Capitol Area Chapter Councilor	1985-present 1985-1987
Association of Government Toxicologists Councilor	1986-2006 1987-1988

VI. Additional Experience/responsibilities- (partial list)

United Nations:

World Health Organization

OECD (Organization for Economic Cooperation and Development)

National Toxicology Program-

Toxicology Forum

American Chemistry Council

Midwest Center for Environmental Science and Public Policy

U.S. EPA Advisory Committees

National Academy of Sciences

GreenBlue Member, Board of Directors   2006-present

VII. PRESENTATIONS/SPEECHES/TALKS (Partial List)

1983. Water Contamination. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. May 3.

1984. Water Contamination. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April 23.

1984. Water, Water Everywhere: The Office of Water Standards, Criteria, Guidance, and Other NumbersBOrigins and Applications. Presented at an Office of Waste Program Enforcement Seminar. May 17.

1985. EPA's Health Advisory Program. Presented to the meeting of the Water Quality Association's Board of Governors. Washington, DC. April 16.

1985. Drinking Water Contamination. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. May.

1985. Overview of EPA's Risk Assessment Practices-With Emphasis on Water. Presented at the Regional Risk Assessment Conference. Atlanta, GA. June.

1986. EPA's Risk Assessment Practices-With A Focus on Drinking Water. Presented to the  Northeast Public Policy Committee. Boston, MA. February 26.

1986. Water Contamination. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April.

1986. Water Contamination. Presented to the class enrolled in "Introduction to Toxic Materials" American University. Washington, DC. April 23.

1986. Reproductive Toxins in the Workplace. Presented to the students in the Department of Obstetrics and Gynecology of the College of Medicine, SUNY-Syracuse. Syracuse, NY. May 21.

1986. Pesticide Registration and the Safe Drinking Water Act: A Federal Perspective for Health Standard Setting. Presented at conference entitled "Pesticides and Groundwater: A Health Concern for the Midwest."  St. Paul, MN. October 16-17.

1986. Federal Regulatory Agency Assessment of Acrylonitrile: The U.S. Environmental Protection Agency's Approach. Presented at the Second Workshop on Pragmatics of Risk Assessment. Cosponsored by the Association of Government Toxicologists and the National Capital Area Chapter of the Society of Toxicology. Bethesda, MD. October 28-29.

1986. Water Contamination. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April.

1986. Pesticides, Potatoes and Problems. Presented at the workshop of the New England Interstate Water Pollution Control Commission. Andover, MA. November.

1987. Scientific/Technical Careers Advisory Committee: Are You WISE to What's In It For You? Presented to the meeting of WISE.  Washington, DC. September 29.

1988. Applications of Risk Assessment at EPA: Alphabet Soup and the Numbers Game. Presented to the staff at CH2MHill. June 10.

1988. Water. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April 20.

1989. Career Possibilities for Women Scientists at EPA.  Presented at the WISE meeting. Washington, DC. April 5.

1989. Water. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April.

1989. Risk Assessment Methods for Pesticides in Food and Drinking Water. Presented to the Pesticide Review Council of the Florida Department of Agriculture and Consumer Services. Tallahassee, FL. July 7.

1989. Federal Government Perspectives on Risk Assessment: The U.S. Environmental Protection Agency. Presented at the American Industrial Hygiene Association Toxicology Symposium. Williamsburg, VA. August 17.

1989. EPA's Risk Assessment on Diaminozide. Presented at the meeting of the Subcommittee on Environmental Carcinogenesis of the National Cancer Advisory Board.  Bethesda, MD. September 18.

1989. Neurotoxicity. Briefing for the Assistant Administrator for OPTS in preparation for her testimony before the October 3 hearing of the Subcommittee on Toxic Substances, Environmental Oversight, Research and Development of the Senate Committee on Environment and Public Works. Washington, DC. September 25.

1989. Cancer Risk. Presented at the 1989 Washington Conference on Risk Assessment sponsored by CEEM. Washington, DC. September 26.

1989. FIFRA 88: How Much More Will We Know About Pesticides in 1997 Than We Know No Know? Presented to the National Capital Area Chapter of the Society of Toxicology. Bethesda, MD. December 6.

1990. The Regulatory and Risk Management Process. Presented in "Toxicity of Agents: Pesticides," in a Continuing Education Course of the Society of Toxicology at its Annual Meeting. Miami Beach, FL. February 12.

1990. Careers and Opportunities in Governmental/Regulatory Toxicology. Presented at the Careers Seminar of the Society of Toxicology.  Miami Beach, FL. February 12.

1990. EPA's Risk Assessment for Malathion. Presented to the California State Assembly's Committee of the Whole. Sacramento, CA. February.

1990. Dietary Exposure. A briefing presented to the Assistant Administrator, OPTS. Washington, DC. March 5.

1990. "Negligible Risk"and Risk Assessment Decision Making: Risk Assessment Methods for Pesticides in Food and Drinking Water. Presented at the Eighth Annual Pesticide Forum of the National Coalition Against the Misuse of Pesticides. Washington, DC. March 24.

1990. Water. Presented in the Course "Environmental Toxicology." NIH Graduate School.  Bethesda, MD. April.

1990. Career Advancement for Women at EPA. Presented to the Office of Municipal Pollution Control. Washington, DC. May 9.

1990. Risk Assessment Methods for Pesticides in Food and Drinking Water. Presented to Senior Management, USDA. Washington, DC. July 2.

1990.The Perspective of the U.S. Environmental Protection Agency on the Risk Assessment Problems of Peroxisome Proliferators. Presented at the Summer Toxicology Forum. Aspen, CO. July 16.

1990. Regulations on Chemical Carcinogenesis of the Environmental Protection Agency (EPA). Presented at the Satellite Symposium on Risk Assessment in Chemical Carcinogenesis at the Heidelberg Academy for the Humanities and Sciences. Heidelberg, Germany. August 24-25.

1990. Exposure Assessment Methods for Pesticides.  Presented to the Risk Assessment Council Subcommittee on the Maximally-Exposed Individual. Washington, DC. September 26.

1990. Welcome and Introduction. ILSI Seminar on Human Risks to Peroxisomal Proliferating Agents. Arlington, VA. December 18.

1991. Applications of Risk Assessment. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April 15.

1991. Regulatory Concerns of the United States Environmental Protection Agency. Presented at the International Workshop on Clinical Pathology Testing in Preclinical Safety Assessment. Washington, DC. July 27.

1991. Regulatory Perspectives on Carcinogenesis of Peroxisome Proliferators. Presented at the 92^nd Meeting of the Interagency Collaborative Group on Environmental Carcinogenesis. Bethesda, MD. November 13.

1991. Aggregate Cancer Risks: Evidence and Issues.  Presented in a session on Aggregate Risk at the Annual Meeting of the Society for Risk Analysis. Baltimore, MD. December 10.

1992. Regulatory Perspective on Mechanistic Information for Carcinogenicity Studies. Presented at the ILSI annual meeting. Miami Beach, FL. January.

1992. Risk Assessment for Pesticide Exposure in Food.  Presented in the Pharmacology/Morphology session of the PMA Foundation Annual Awardee Meeting. Washington, DC. January 23.

1992. EPA View on Long Term Bioassay Needs for Pesticides.  Presented at the Winter Toxicology Forum. Washington, DC. February.

1992. Toxicity Information Requirements for Chemicals.  Presented in a session on "Toxicology and Animal Rights" at the National Meeting of the American Institute of Chemists. San Antonio, TX.  February 22.

1992. Role of Federal Users of Nutrition Monitoring Data-EPA. Presented at the first meeting of the National Nutrition Monitoring Advisory Council. Washington, DC. February 27.

1992. Design of Studies to Obtain Pharmacokinetic Data for Risk Assessment. Presented at a workshop entitled "Pharmacokinetics: Defining Dosimetry for Risk Assessment" sponsored by the National Academy of Sciences. Washington, DC. March 4.

1992. Definition of a Carcinogen or How Do We Tell If It Is a Carcinogen? Presented at an ILSI Japan symposium entitled AAssessing Human Cancer Risks: The State of the Science. Tokyo and Osaka, Japan. April 13 and April 16.

1992. EPA's Risk Assessment Approach for Cancer. Presented in a panel discussion of the session entitled "Background to Existing International Divergency in Pesticide Regulation: Why Different Regulatory Decisions When the Scientific Information Base is Similar? Part I-Human Risk Assessment" at the workshop entitled "The Role of Science in Pesticide Management." Stockholm, Sweden. May 21.

1993. Applications of Risk Assessment. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April 26.

1993. Human Health Risk Assessment for Pesticides Under FIFRA/FFDCA.   Presented in the GWU Course "Environmental and Occupational Health Policy." Washington, DC. June 3.

1993. Status Report on the Federal Government's Response to the National Academy of Sciences' Report on Pesticides in the Diets of Infants and Children. Presented at the Fall Conference of the National Agricultural Chemicals Association. Washington, DC October 29.

1994. Update on the Federal Government's Response to the National Academy of Sciences' Report. Presented to the American Bar Association Subcommittee on Pesticides. Washington, DC. January 25.

1994. Prospects for International Harmonization of Risk Assessment Methodologies for Human Health. In: International Harmonization: Update on Scientific and Regulatory Issues. Part II: Toxic Substances and Environmental Issues. A Continuing Education Course of the Society of Toxicology. March 13.

1994. Pesticides as Hormone Disruptors. Presented at the Risk Assessment Forum Colloquium on Environmental Hormones. April 13.

1994. Part I:Applications of Risk Assessment. Part II: Environmental Hormones-Endocrine Disruptors. Presented in the Course "Environmental Toxicology." NIH Graduate School. Bethesda, MD. April 18.

1994. Feeding Your Children Five-a-day: Good Nutrition or Health Risk? Presented at the WISE Spring Luncheon. Washington, DC. June 9.

1994. What is the Federal Government Doing About the NAS Report Pesticides in the Diets of Infants and Children? Presented at the Office of Pesticide Programs' Workshop. Arlington, VA June 13.

1994. International Harmonization of Health Risk Assessment: The U.S. EPA Perspective. Presented at the First Annual Conference on Environmental Computing and Information Technology. Arlington, VA. June 10.

1994. EPA's Risk Assessment Practices for Food. Presented at the briefing sponsored by the Congressional Research Service on "Comparative Risk Analysis for Foods: The Roles of EPA and FDA." Washington, DC. June 30.

1994. Trends in Cancer Risk Assessment. Presented at the IUPAC Meeting. Washington, DC. July 5.

1994. EPA OPP's Activities Concerning Children's Exposure to Pesticides and of "Reinventing Tolerances." Presented at the ASTHO Environment Committee Meeting. Washington, DC. July 20.

1994. Pesticides: An Estrogenic Effect? What is EPA Doing About Them? Presented at the Annual Meeting of the Chemical Producers and Distributors Association. Vancouver, BC. August 8.

1995. Science, Policy and Pesticides: What's Hot, What's Not. 1995. Presented in the ILSI Seminar series at the Brookings Institution. Washington, DC. February 25.

1995. Should We Relax Some Environmental Regulations and Possibly Put at Risk Public Health and Future Lives? Presenting the side perceiving that we are not overregulated in a Roundtable session on "Protecting the Food Supply from Environmental Contaminants: Scientific and Economic Considerations" at the Annual Meeting of the Society of Toxicology. Baltimore, MD. March 6.

1995. Impact of the Delaney Clause in the EPA. Presented at the Second International Conference of the International Federation of Societies of Toxicologic Pathologists. Tours, France. April 26.

1995. The Faceless Bureaucrat. Presented at the Alumni Career Path Day of the UTMB Graduate School Career Forum. May 5.

1995. Peroxisome Proliferator-induced Hepatocarcinogenesis: An EPA Perspective on Risk Assessment. Presented at the International Symposium entitled "Peroxisomes: Biology and Role in Toxicology and Disease." Aspen, CO. July 2.

1995. Determining the "If" and "How" of Carcinogenesis: A Vision of the Future. Presented at the 1995 FDA Science Symposium "Developing Alternative In Vivo Approaches for Assessment of Carcinogenicity." Bethesda, MD. December 6-7.

1995. An EPA Perspective on Assessing Risk to the Carcinogenicity of Peroxisome Proliferator-induce Carcinogenesis. Presented the ILSI Workshop on "Do Peroxisome Proliferating Compounds Pose a Hepatocarcinogenic Risk to Humans?" Arlington, VA. December 13-14.

1996. Dietary Risk from Exposure to Pesticide Mixtures.  Presented in a Current Issues in Risk Assessment session on "Chemical Mixtures: Safety and Regulatory Policy Issues" at the 1996 ILSI Annual Meeting. Cancun, Mexico. January 23.

1996. EPA's Endocrine Disruptor Screening Program-Progress to Date. Presented to the Endocrine Issues Coalition of Chemical Manufacturers' Association. Arlington, VA. February 15.

1996. Risk Management Using Probabilistic Model-based Assessments-The EPA Perspective. Presented in a symposium entitled "Risk Assessment and Risk Management of Worker Exposures to Pesticides: The Next Generation" at the Annual Meeting of the Society of Toxicology. Anaheim, CA. March.

1996. Incorporating New Science into Environmental Health Risk Decisions. Presented at the CIIT 20^th Anniversary Symposium "The Chemical Industry, Health Sciences and Risk Regulations." Durham, NC.  April 30.

1996. Comments on Proposed EPA Cancer Guidelines.  Presented as a member of Panel on Hazard Identification/Risk Characterization/Weight of Evidence at the ILSI/RFF/EPA Forum on Cancer Risk Assessment Guidelines. Washington, DC. May 6.

1996. Assessing Animal Health Products: The EPA Role. Presented at the conference of Scientists' Center for Animal Welfare entitled "Animal Welfare and Toxicology/Safety Studies: Current Issues and Trends for the Next Century." Baltimore, MD. June 10.

1996. ILSI's Dose Selection Project-An Update. Presented at the Summer Toxicology Forum.  Aspen, CO. July 12.

1996. FQPA Risk Assessment Requirements. Presented at the Joint ACPA/ABA Conference on the Food Safety Amendments. September

1996. EPA's Proposed Guidelines for Carcinogen Risk Assessment. Presented to the WHO IPCS staff. Geneva, Switzerland. September 13.

1996. Part I-EPA's Proposed Guidelines for Carcinogen Risk Assessment. Part II-The Food Quality Protection Act. Presented to the Joint Meeting on Pesticide Residues. Rome, Italy. September 19.

1996. Special Panel Discussion: Endocrine Disruptors.  Presented at a workshop entitles "Pesticide Regulation: Preparing for 2000" sponsored by Executive Enterprises. Washington, DC. October 2.

1996. Risk Assessment for Regulatory Decision Making: The EPA Perspective. Presented at the IBC International Environmental Congress entitled "Endocrine Disrupters-Advances in Measuring and Analysing Their Effects." Washington, DC. October 8.

1996. Risk Assessment and Regulatory Issues Related to Endocrine Disruptors. Presented at the meeting of the Environmental Group of the Organizational Resources Counselors, Inc. Washington, DC. October 10.

1996. The FQPA-Emphasis on Risk Assessment Issues.  Presented to the National Capital Area Chapter of the Society for Risk Analysis. Washington, DC. October 17.

1996. Overview: Food Quality Protection Act of 1996. Presented to the FIFRA Scientific Advisory Panel. Arlington, VA. October 29.

1996. EPA's Risk Assessment Policies. Presented as member of a panel on "Risk Assessment: Application to Children's Health" at the annual meeting of the American Public Health Association. New York, NY. November 20.

1996. Regulatory Case Studies-EPA Office of Pesticide Programs in a session entitled "Use of Pre-carcinogenicity Data in Carcinogenicity Predictions, Classifications, and Risk Assessment" at the 10^th International Barton Creek Conference on Carcinogenesis and Risk Assessment on "New Approaches for Assessing the Carcinogenic Potential of Chemicals." Austin, TX. December 7.

1997. Endocrine Disruptor Risk Characterization: An EPA Perspective. Presented at the ISRTP Symposium entitled "Assessing the Risk of Adverse Endocrine-mediated Effects." Research Triangle Park, NC.  January 14.

1997. The Food Quality Protection Act of 1996. Presented to the Executive Committee of the Science Advisory Board. Washington, DC.  January 15.

1997. Use of Data from Transgenic Animals in Cancer Risk Assessment: An EPA Perspective. Presented as a member of a panel in a roundtable session entitled "Should Carcinogenesis Data from Transgenic Animals be Applied in Regulation. If so, How? Annual Meeting of the Society of Toxicology." Cincinnati, OH. March 11.

1997. Summary and Regulatory Implications. Presented in a workshop entitled "Use of Mode of Action Information in Cancer Risk Assessment: Implementing EPA's Proposed Cancer Guidelines" at the Annual Meeting of the Society of Toxicology. Cincinnati,OH. March 13.

1997. ILSI's Dose Selection Project. Presented at the ILSI Brookings Institution Seminar Series. April 3.

1997. Endocrine Disruptors: Risk Assessment and Regulatory Issues. Presented to the Conference Board's Chief Environmental Health and Safety Officers Council I. Washington, DC. April 10.

1997. Risk Assessment for Regulatory Decision Making: The EPA Perspective. Presented at the IBC International Environmental Congress entitled " Endocrine Disrupters-Advances in Measuring and Analysing Their Effects." Washington, DC. May 5.

1997. Endocrine Disruptors: Risk Assessment and Regulatory Issues. Presented at the TAPPI Environmental Division Conference.  Minneapolis, MN. May 7.

 1997. The Food Quality Protection Act of 1996. Presented to the Office of Water's FSTRAC. Washington, DC. May 8.

1997. FQPA Science Issues. Presented to the ILSI Residue Committee. Washington, DC. May 15.

1997. EPA's Legislative Mandate w/Background. Presented in the Endocrine Disruptors Roundtable entitled "Endocrine Disrupting Chemicals-Implications for Human Effects" at the American Industrial Hygiene Conference and Exposition. Dallas, TX. May 19.

1997. EPA's Endocrine Disruptor Screening Program-Progress to Date. Presented to the Endocrine Issues Coalition of the Chemical Manufacturers Association. Arlington, VA. May.

1997. EPA's Evolving Endocrine Disruptor Policy. Presented at the EDC Information Network's Workshop on "The Science, Policy, and Law on Suspected Endocrine Disrupting Chemicals."  Washington, DC. June 20.

1997. (When) Cancer Risk Assessment Should Not Incorporate the Concept of a Threshold. Presented in a debate session entitled "Cancer Risk Assessment Should Incorporate the Concept of a Threshold" at the 36^th European Congress of Toxicology-Diversification in Toxicology: Man and Environment. Aarhus, Denmark. June 27.

 1997. Use of Data from Transgenic Animals in Cancer Risk Assessment: An EPA Perspective. Presented as a member of a panel in a session entitled ATransgenic Models for Predicting Chemical Carcinogenicity: Current Status, Issues, and Implications of Their Use in Carcinogenicity Assessments. Summer Toxicology Forum. Aspen, CO. July 8.

1997. EDSTAC-Environmental Estrogens Tiered Testing-An Update (Endocrine Disruptors: EPA's Interim Policy and EDSTAC Activities). Presented at the Summer Toxicology Forum. Aspen, CO. July 11.

1997. Use of Mechanistic Data in Cancer Risk Assessment.  Presented at the Aspen Cancer Conference. Aspen, CO. July 15.

1997. Endocrine Disruptors: Risk Assessment and Regulatory Issues. Presented at the 1997 Annual Meeting of the Science and Technology Section of the American Bar Association in the session entitled "The New Cancer Scare of the 1990's-Endocrine Disruptors: Paying Havoc with the Human Hormone System." San Francisco, CA. August 4.

1997. FQPA Science Issues. Presented at the ILSI workshop on "Common Mechanism of Toxicity: A Case Study of Organophosphorus Pesticides." Washington, DC. October 21.

1997. ICCVAM: Future Directions. Presented in a session entitled "Partnership Opportunities/Advisory Committee Role" at the meeting of the ICCVAM Advisory Committee on Alternative Toxicological Methods.  RTP, NC (by telephone). November 7.

1997. Introduction to Risk Characterization. Presented in a session on "Risk Characterization-Approaches to Characterizing Risk of Endocrine Modulators from Dietary Exposures" at the ILSI Conference on Human Diet and Endocrine Modulation: Estrogenic and Androgenic Effects.  Fairfax, VA. November 21.

1997. U.S. EPA's Research Planning Process-How Well Does it Work? Presented at the 1997 FDA Forum on Regulatory Sciences: A Culture of Science at FDA: Partnerships in Research and Review. Bethesda, MD. December 9.

1998. FQPA (Science) Policy Issues and the EPA. Presented in a symposium entitled "The FQPA (Food Quality Protection Act of 1996): The Challenging New Aggregate Exposure Risk Assessments of the 1996 FQPA" at the Annual Meeting of the Society of Toxicology. Seattle, WA. March 3.

1998. Implementation: Screening and Testing Program.  Presented in a workshop entitled "Endocrine Identification: The EDSTAC Process"at the Annual Meeting of the Society of Toxicology. Seattle, WA. March 4.

1998. EDSTAC Update. Presented at the Endocrine Issues Science Forum's session on "Emerging EDSTAC Report and Recommendations." Washington, DC. March 19.

1998. Pesticide Tolerances: Are Children at Higher Risk?  Presented in a session entitled "Environmental Science and Policy" at the 1998 Ceres Conference on Politicizing Science: What Price Public Policy?  How Nutrition and Food Issues Reach the Public. Chantilly, VA. April 3.

1998. How the FQPA Requires the EPA to Address Endocrine Disruption. Presented at a Forum of the Society for Risk Analysis entitled "Protecting Sensitive Groups as Mandated by the FQPA and the SDWA: Can Science Meet the Challenge?" Alexandria, VA. June 29.

1998. Endocrine Modulators: Risk Characterisation and Assessment. Presented in a session entitled "Endocrine Modulators in the Environment" at the 3^rd International Conference on the International Federation of Societies of Toxicologic Pathologists. Cambridge, England. August 18.

1998. New Legislation, Regulations and Guidelines. Presented in a session entitled "New Legislation and Regulations: Background and Perspectives" at the 16^th International Neurotoxicology Conference. Little Rock, AK. September 13.

1998. Assessing Risk: The Revolution is UnderwayCFQPA Science Issues.  Presented at the 6^th Section Fall Meeting of the ABA Section on Natural Resources, Energy, and Environmental Law. Hilton Head, SC. October 9.

1998. EPA Priorities: Indirect Risk and Endocrine Disruptors. Presented at the Fall Conference of the RCRA Policy Forum.  Arlington, VA. October 22.

1998. EPA's Endocrine Disruptors Screening and Testing Program: Implementation. Presented to the International Hydrolyzed Protein Council. Washington, DC. October 27.

1998. FQPA Implementation: Science Issues. Presented to the Science and Research Work Group of the U.S. EPA Children's Health Protection Advisory Committee in a session entitled "Perspectives on Existing Methods for Incorporating Children's Health Issues in the Risk Assessment Process." New Carrollton, MD. November 4.

1998. Status of FQPA Science Issues at EPA. Presented at the Pesticide Regulation Conference sponsored by Executive Enterprises. Washington, DC. November 4.

1998. Status of FQPA Science Issues at EPA. Presented at the Pesticide Regulations Conference sponsored by Government Institutes. December 2.

1999. FQPA Science Issues: Common Mechanism of Toxicity and Cumulative Risk Assessment. Presented at a Roundtable entitled "The Challenges of Using Common Mechanism of Toxicity in Chemical Regulation" at the Annual Meeting of the Society of Toxicology. New Orleans, LA. March 17.

1999. FQPA Science Issues: The FQPA 10X Safety Factor.  Presented in a symposium entitled "Issues Session: As Additional Ten-fold Safety Factor for Children: Is This Needed?" at the Annual Meeting of the Society of Toxicology. New Orleans, LA. March 18.

1999. Common Mechanism and Cumulative Risk Assessment.  Presented in a session entitled "Cumulative Risk and Common Mechanism" at the ISRTP and CAST workshop on "The FQPA: A Challenge for Science Policy and Pesticide Regulation." Fairfax, VA. March 24.

1999. Introductory Remarks. Presented at the Toxicology Forum's workshop on "Dose-response Consideration for Potential Endocrine Active Substances." Washington, DC. April 15-16.

1999. Endocrine Disruptor Screening and Testing:Validation and Regulatory Implementation. Presented in a session on Endocrine Disrupters at the EU/US Environmental Chemicals Conference. Cernobbio, Italy. May 20.

1999. U.S. Research Activities. Presented in a session on Endocrine Disrupters at the EU/US Environmental Chemicals Conference. Cernobbio, Italy. May 20.

1999. FQPA Science Issues. Presented in the FQPA Symposium at the Annual Meeting of the Institute of Food Technologists. Chicago. July.

1999. The Office of Pesticide Programs' Policy on Determination of the Appropriate FQPA Safety Factor(s) For Use in the Tolerance-setting Process. Presented to the FIFRA Scientific Advisory Panel. Arlington, VA. May 25

1999. Update on Food Quality Protection Act Science Issues.  Presented to the FAO/WHO Joint Meeting on Pesticide Residues. Rome, Italy.  September 27

1999. Endocrine Disruptor Screening and Testing Program: Validation and Regulatory Implementation. Presented at the SEFA meeting on Endocrine Disruptors and the Environment. Nantes, France. October 8.

1999. Endocrine Disruptor Screening and Testing Program: Validation and Regulatory Implementation. Presented at the SEHSC. San Antonio, TX. November 3.

1999. Cumulative Risk Assessment for Pesticides Acting Through a Common Mechanism. Presented in symposium entitled "Mixtures and Common Mechanisms of Endocrine Activity: A New Millennium for Controversy" at the Annual Meeting of the American College of Toxicology. McLean, VA.  November 8.

1999. Current Policy Regarding the Implementation of the FQPA 10X Safety Factor. Presented in a symposium entitled "Food Quality Protection Act-Update" at the Annual Meeting of the American College of Toxicology. McLean, VA. November 9.

2000. Update on the EPA FQPA 10X Policy. Presented at the Winter Toxicology Forum. Washington, DC. February 8.

2000. Introduction to the NRC/NAS Report on Hormonally-active Agents. Presented at the Winter Toxicology Forum.  Washington, DC. February 8.

2000. Role of Human Research in the Office of Pesticide Programs. Presented at the Annual Meeting of the Society of Toxicology.  Philadelphia, PA. March 23.

2000. The FQPA Safety Factor. How much is Science? How much is Sociology? Presented at the Fourth Annual Workshop on Evaluation of Uncertainty/Safety Factors in Health Risk Assessment. Nutley, NJ. May 3.

2000. Overview of values at risk, objectives of a risk assessment, assessment questions and current use of indicators. Presented in a session on Endocrine Disrupting Chemicals at the 5^th Annual NHEERL Symposium-Indicators in Health and Ecological Risk Assessment. Research Triangle Park, NC. June 6.

2000. Update on the Food Quality Protection Act. Presented at the Summer Toxicology Forum meeting. Aspen, Colorado. July 11.

2000. Update on the Endocrine Disruptor Screening Program. Presented at the Summer Toxicology Forum meeting. Aspen, Colorado. July 11.

2000. Chlorinated pesticides-the Regulatory Structure.  Presented to the Ethics and Sustainability Dialogue Group's meeting on Issues Related to Chlorinated Pesticides. Orlando, FL. July 20.

2000. Endocrine Disruptors: Risk Assessment and Regulatory Activities. Presented in a session on endocrine disruptors at the Association of State and Territorial Solid Waste Management Officials' 2000 Superfund Managers Symposium. Scottsdale, AZ. August 14.

2000. Regulatory problems of pesticides. Presented at the University of Oporto's Food Safety Conference. Oporto, Portugal. November 10.

2001. Potential Health Hazards in the Food Supply-Chemicals: A Preliminary Analysis. Resources for the Future Symposium on Food Safety. Washington, DC. April.

2001. Cholinesterase-inhibiting Insecticides: A Case Study. Duke University Spring Symposium of the Interdisciplinary Toxicology Program.  Durham, NC. April.

2001. Precautionary Principles: Is there a role for risk assessment? American College of Toxicology annual meeting.  Washington, DC. November 5.

2002. Determination of Acceptable Exposure Levels for Humans for Endocrine Active Substances: Use of Animal Models. Presented at the IUPAC-SCOPE International Symposium on Endocrine Active Substances. Yokohama, Japan. November 19.

2002. Human Subjects Research in Environmental Policy. Presented to the National Academy of Science's Committee on Use of Third Party Toxicity Research with Human Participants. Washington, DC. December 17.

2003. Enhancing the rigor of cancer risk assessment.  Presented at the February Toxicology Forum. Washington, DC. February 3.

2003. Human Subjects Research in Regulatory Policy. Presented at the Annual Meeting of the International Association of Food Protection, New Orleans, LA. August 12.

2004. Nutraceuticals should be regulated as drugs. The argument for the proposition. Presented at the annual meeting of the Society of Toxicology, Baltimore, MD. March 10.

2004. Overview of Projects of the ILSI Risk Science Institute. Presented to the National Academy of Sciences Committee on Toxicity Testing. July.

2004. Nutraceuticals should be regulated as drugs. The argument for the proposition. Presented at the tenth meeting of the International Union of Toxicologists, Tempere, Finland. July 13.

2004. Characterizing Carcinogenic Potential. Presented in the symposium entitled

Framework for Use of Screening Tools for Potentially Toxic Chemicals in Context-Based Decision-Making at the annual meeting of the Society for Risk Analysis, Palm Springs, CA. December.

2004. Expanding the MOA/Human Relevance Framework. Presented in the symposium entitled Cancer/Non-Cancer Harmonization: Use of Mode of Action Data at the annual meeting of the Society for Risk Analysis, Palm Springs, CA. December.

2005. Application of Developmental Neurotoxicity Testing to Public Health Protection. Presented in a symposium entitled An Evaluation and Interpretation of Neurodevelopmental Endpoints for Human Health Risk Assessment at the annual meeting of the Teratology Society, St. Pete's Beach, FL. June 27.

2006. Introduction to the regulatory context of DNA adducts. Presented in a workshop sponsored by the ACC North American Adducts Research and Risk Assessment Coordinating Committee. Baltimore, MD. October 23.

2006. Evaluating the human relevance of modes of action in animals. Presented as a training workshop at the 2006 meeting of the Society for Risk Analysis. Baltimore, MD. December 3.

2007. FQPA: "It's a Good Thing" (for kids).  Arguing the PRO position in a debate on the question: FQPA has enhanced the protection of children's health. Presented at the meeting of the Risk Assessment Specialty Section at the annual meeting of the Society of Toxicology. Charlotte, NC. March 26.

2007. Evaluating the human relevance of modes of action in animals. Presented as a training workshop. Washington, DC. April 16.

VIII. PUBLICATIONS

Fenner-Crisp, P. 1992. Regulatory Concerns of the United States Environmental Protection Agency. Toxicol. Pathol. 20:523-525.

Fenner-Crisp, P. 1995. Editorial: Urinary Bladder Carcinogenesis. Food Chem. Toxic. 33(9):699

Fenner-Crisp, P. 1995. PesticidesBThe NAS Report: How Can the Recommendations be Implemented? Environ. Health Perspect. 103 (Suppl 6): 159-162.

Fenner-Crisp, P. 1996. Impact of the Delaney Clause in the EPA. Exp. Toxic. Pathol. 48:199-200.

Fenner-Crisp, PA. 1996. Regulatory Implications: U.S. Environmental Protection Agency. In the Proceedings of the International Symposium entitled "Peroxisomes: Biology and Role in Toxicology and Disease." Ann. N.Y. Acad. Sci. 804: 636-640.

Fenner-Crisp, PA. 1997. Risk Assessment 'A la Mode'-How Much Data is Enough? Risk Policy Report. 3(2): 19-21.

Fenner-Crisp, PA. 1997. Book Review of Our Children's Toxic Legacy: How Science and Law Fail to Protect Us From Pesticides. John Wargo Yale University Press. New Haven and London. Bioscience

Williams, GM., Karbe, E., Fenner-Crisp, P., Iatropoulos, MJ, and JH Weisburger. 1996. Risk Assessment of Carcinogens in Food with Special Consideration of Non-genotoxic Carcinogens. Exp. Toxic. Pathol. 48: 209-215.

Fenner-Crisp, P.A. 1998. New Legislation, Regulations and Guidelines. NeuroToxicology 20(1): 12. (Abstract)

Fenner-Crisp, P.A., Maciorowski AM and Timm GE. 2000. The Endocrine Disruptor Screening Program Developed by the U.S. Environmental Protection Agency. Ecotoxicology 9: 85-91.

Fenner-Crisp, PA. 2000.  Endocrine modulators: risk characterization and assessment.  Toxicol. Pathol. 28(3): 438-440.

Fenner-Crisp, P.A. 2000. FQPA Science Issues: Common Mechanism and Cumulative Risk Assessment. Reg. Tox. Pharmacol. 31:308-310.

Fenner-Crisp, P.A. 2001. Regulatory problems of pesticides. Published in the Proceedings of the Food Safety Conference, November 10-11, 2000, Oporto, Portugal.

Fenner-Crisp, PA. 2001. Chapter 31: The Regulatory Process in: Handbook of Pesticide Toxicology, R. Krieger, ed., second edition, Academic Press.

Fenner-Crisp, PA. 2001. Potential Health Hazards in the Food Supply-Chemicals: A Preliminary Analysis. Chapter in the Proceedings of the Resources for the Future Symposium on Food Safety, April, Washington, DC.

Kanno, J, Onyon L, Haseman J, Fenner-Crisp P, Ashby J, Owens W. 2001. The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: Phase 1. Environ. Health Perspec. 109(8):785-794.

Fenner-Crisp, P.A. 2003. Determination of acceptable exposure levels for humans for endocrine active substances: Use of animal models. Pure and Appl. Chem. 75(11-12): 2143-2149.

Cohen, S.M., M.E. Meek, J.E. Klaunig, D.E.Patton and P.A. Fenner-Crisp. 2003. The human relevance of information on carcinogenic modes of action: Overview. Crit. Rev. Toxicol. 33(6): 581-590.

Klaunig, J.E., M.A. Babich, K.P. Baetcke, J.C. Cook, J.C. Corton, R.M. David, J.D. DeLuca, D.Y. Lai, R.H. McKee, J.M. Peters, R.A. Roberts and P.A. Fenner-Crisp. 2003. PPARα agonist-induced rodent tumors: Modes of action and human relevance. Crit. Rev. Toxicol. 33(6):655-780.

Daston, G., E. Faustman, G. Ginsburg, P. Fenner-Crisp, S. Olin, B. Sonawane, J. Brickner and W. Breslin. 2004. A framework for assessing risks to children from exposure to environmental agents. Environ, Hlth. A framework for assessing risks to children from exposure to environmental agents. Environ. Hlth. Perspecs. 112(2):238-256.

Seed, J., Carney E., Corley, R., Crofton, K.M., DeSesso, J.M., Foster, P.M.D., Kavlock, R., Kimmel, G., Klaunig, J., Meek, M.E., Preston, R.J., Slikker, W. Jr., Tabacova, S., Williams, G.M., Wiltse, J., Zoeller, R.T., Fenner-Crisp, P.A. and D.E. Patton.  2005. Overview: Using Mode of Action and Life Stage Information to Evaluate the Human Relevance of Animal Toxicity Data. Crit. Rev. Toxicol. 35 (8-9): 663-672.

Carmichael, N.G., Barton, H.A.,Boobis, A.R., Cooper R.L., Dellarco, V.L., Doerrer, N.G., Fenner-Crisp, P.A., Doe, J.E., Lamb, J.C. IV, and T. P. Pastoor.  2005. Agricultural Chemical Safety Assessment:A Multi-sector Approach to the Modernization of Human Safety Requirements. Crit. Rev. Toxicol. 36:1-7.

Cooper, R.L., J.C. Lamb, IV, S. M. Barlow, K. Bentley, A. M. Brady, N.G. Doerrer, D.L. Eisenbrandt, P. A. Fenner-Crisp, R. N. Hines, L. F.H. Irvine, C. A. Kimmel, H. Koeter, A. A. Li, S. L. Makris, L. P. Sheets, G. J.A. Speijers, and K. E. Whitby. 2005. A Tiered Approach to Life Stages Testing for Agricultural Chemical Safety Assessment. Crit. Rev. Toxicol. 36:69-98.

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