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U.S. Department of Health and Human Services

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Research Project: Dose and Image Quality in CT and Cardiovascular Imaging

Cardiovascular disease is considered the leading cause of death in the US, accounting for 38% of all deaths, with an estimated direct and indirect cost of almost $400 billion. Coronary artery disease (CAD) is principally identified and diagnosed using contrast projection cine angiography and cardiac CT imaging. The quality of the imaging modalities is a very important component in CAD treatment planning and follow-up, and in image-guided cardiac and vascular interventions as it directs and influences the physicians’ options and actions.  This project aims at identifying the imaging tasks involved in the diagnosis and therapy of cardiovascular disease and at optimizing image quality for each patient while accounting for patient radiation and contrast agent dose.

 

Schematic showing how a stenosis is generated on the left coronary artery.
Schematic showing how a stenosis is generated on the left coronary artery, then inserted into the heart phantom we developed. The heart phantom is then registered into the virtual family phantom and realistic angiograms are simulated.