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U.S. Department of Health and Human Services

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Research Project: Gender Differences in Drug Release

Contacts: Ji Guo and Kenya Brothers 

Active Materials Lab researchers are examining the potential for gender-based differences in the efficacy of drug eluting stents.  Ongoing investigations are targeting possible effects of gender differences in atherosclerotic plaque.  Current results suggest possible variations in drug release rate and distribution depends on the composition and morphology of the diseased vasculature.  Such information is expected to illuminate clinical experience with existing devices, and to open the door to new domains of product innovation.