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FY 2009 Scientific Publications

  • Arias, H., Santamaria, A., and Ali, S.F. (2009). Pharmacological and neurotoxicological actions mediated by bupropion and diethylpropion. International Review of Neurobiology. 88:223-239.
  • Baek, S., Kweon, O., Kim, S., Baek, D., Chen, J.J., and Cerniglia, C.E. (2009). ClassRHO: A platform for classification of bacterial rieske non-heme iron ring-hydroxylating oxygenases. Journal of Microbiological Methods. 76(3):307-309.
  • Beger, R., Hansen, D.K., Schnackenberg, L., Cross, B.M., Fatollahi, J.J., Lagunero, F.T., Sarnyai, Z., and Boros, L.G. (2009). Single valproic acid treatment inhibits glycogen and RNA ribose turnover while disrupting glucose-derived cholesterol synthesis in liver as revealed by the [U-13C6]-D-glucose tracer in mice. Metabolomics. 5:336-345.
  • Beilke, L.D., Aleksunes, L.M., Holland, R.D., Besselsen, D.G., Beger, R., Klaassen, C.D., and Cherrington, N.J. (2009). Car-mediated changes in bile acid composition contributes to hepatoprotection from LCA-induced liver injury in mice. Drug Metabolism and Disposition. 37(5):1035-1045.
  • Boctor, S.Y. and Ferguson, S.A. (2009). Altered adult locomotor activity in rats from phencyclidine treatment on postnatal days 7,9, and 11, but not repeated ketamine treatment on postnatal day 7. Neurotoxicology. e-pub.
  • Boctor, S.Y. and Ferguson, S.A. (2009). Neonatal NMDA receptor antagonist treatments have no effects on prepulse inhibition of postnatal day 25 Sprague-Dawley rats. Neurotoxicology. 30:151-154.
  • Bowyer, J.F. , Latendresse, J.R., Delongchamp, R.R., Warbritton, A.R., Thomas, M., Divine, B., and Doerge, D.R. (2009). The mRNA expression and histological integrity in rat forebrain motor and sensory regions are minimally affected by acrylamide exposure through drinking water. Toxicology and Applied Pharmacology. 240(3):401-411.
  • Bushel, P.R., Nielsen, D., and Tong, W. (2009). Proceedings of the First International Conference on Toxicogenomics Integrated with Environmental Sciences (TIES-2007). BMC Proceedings. 3(Suppl 2):S1.
  • Cao, Y., Calafat, A.M., Doerge, D.R., Umbach, D., Bernbaum, J.C., Twaddle, N.C., Ye, X., and Rogan, W.J. (2009). Isoflavones in urine, saliva and blood of infants: data from a pilot study on the estrogenic activity of soy formula. Journal of Exposure Science and Environmental Epidemiology. 19(2):223-234.
  • Chamberlain, P.L., Cerniglia, C.E., and Mclean, J. Narasin. 70th Joint FAO/WHO Expert Committee on Food Additives.
  • Chen, H., Xu, H., Heinze, T.M., and Cerniglia, C.E. (2009). Decolorization of water and oil-soluble azo dyes by Lactobacillus acidophilus and Lactobacillus fermentum. Journal of Industrial Microbiology & Biotechnology. e-pub.
  • Chen, T., Heflich, R.H., Moore, M., and Mei, N. (2009). Differential mutagenicity of aflatoxin B(1) in liver of neonatal and adult mice. Environmental Molecular Mutagenesis. e-pub.
  • Delclos, K.B. , Weis, C.C., Bucci, T.J., Olson, G.R., Mellick, P.W., Sadovova, N.V., Latendresse, J.R., Thorn, B.T., and Newbold, R. (2009). Overlapping but distinct effects of genistein and ethinyl estradiol (EE(2)) in female Sprague-Dawley rats in multigenerational reproductive and chronic toxicity studies. Reproductive Toxicology. 27(2):117-132.
  • Dobrovolsky, V.N., Boctor, S.Y., Twaddle, N.C., Doerge, D.R., Bishop, M.E., Manjanatha, M., Kimoto, T., Miura, D., Heflich, R.H., and Ferguson, S.A. (2009). Flow cytometric detection of PIG-A mutant red blood cells using an erythroid-specific antibody: application of the method for evaluating the in vivo genotoxicity of methylphenidate in adolescent rats. Environmental and Molecular Mutagenesis. e-pub.
  • Dobrovolsky, V.N., Shaddock, J.G., Mittelstaedt, R.A., Manjanatha, M., Miura, D., Uchikawa, M., Mattison, D., and Morris, S.M. (2009). Evaluation of Macaca mulatta as a model for genotoxicity studies. Mutation Research. 673(1):21-28.
  • Espandiari, P., Rosenzweig, B., Zhang, J., Zhou, Y., Schnackenberg, L., Vaidya, V.S., Goering, P.L., Brown, R.P., Bonventre, J.V., Mahjoob, K., Holland, R.D., Beger, R.D., Thompson, K., Hanig, J., and Sadrieh, N. (2009). Age-related differences in susceptibility to cisplatin-induced renal toxicity. Journal of Applied Toxicology. e-pub.
  • Fan, X., Fang, H., Hong, H., Perkins, R., Shi, L., and Tong, W. (2008). Correlation analysis of external RNA controls reveals its utility for assessment of microarray assay. Analytical Biochemistry. 385:203-207.
  • Fan, X., Shi, L. , Fang, H. , Harris, S. , Perkins, R., and Tong, W. (2009). Investigation of reproducibility of differentially expressed genes in DNA microarrays through statistical simulation. BMC Proceedings. 3(Suppl 2):S4.
  • Fang, H., Harris, S.C., Su, Z., Chen, M., Qian, F., Shi, L., Arasappan, D., Ge, W., Fan, X., Hong, H., Xu, Z., Turner, S.A., Bishop, M.E., Jackson, M.A., Perkins, R.G., and Tong, W. (2009). FDA bioinformatics tool for public use—ArrayTrack™. Regulatory Research Perspectives. 8(1).
  • Fang, J. and Beland, F.A. (2009). Long-term exposure to zidovudine delays cell cycle progression, induces apoptosis, and decreases telomerase activity in human hepatocytes. Toxicological Sciences. 111(1):120-30.
  • Feng, J., Heinze, T.M., Xu, H., Cerniglia, C.E., and Chen, H. (2009). Evidence for significantly enhancing reduction of azo dyes in Escherichia coli by expressed cytoplasmic azoreductase (AzoA) of Enterococcus faecalis. Protein & Peptide Letters. e-pub.
  • Ferguson, S.A. and Boctor, S.Y. (2009). Use of food wafers for multiple daily oral treatments in young rats. Journal of the American Association of Laboratory Animal Science. 48:292-295.
  • Ferguson, S.A., Delclos, K.B. , Newbold, R.R. a Flynn, K.M. (2009). Few effects of multi-generational dietary exposure to genistein or nonylphenol on sodium solution in male and female Sprague-Dawley rats. Neurotoxicology and Teratology. 31:143-148.
  • Ferguson, S.A., Garey, J.D., Smith, M.E., and Paule, M.G. (2008). Pre and postnatal acrylamide treatment has few effects on preweaning behaviors and developmental landmarks in rats. Neurotoxicology and Teratology.
  • Ferguson, S.A., Gopee, N., Paule, M.G., and Howard, P. (2009). Female mini-pig performance of temporal response differentiation, incremental repeated acquisition, and progressive ration operant tasks. Behavioural Processes. 80:28-34.
  • Foley, S.L., Lynne, A.M., and Nayak, R.R. (2009). Molecular typing methodologies for microbial source tracking and epidemiological investigations of Gram-negative bacterial foodborne pathogens. Infection, Genetics and Evolution. 9:430-440.
  • Foley, S.L., Lynne, A.M., and Nayak, R.R. Molecular typing methods of enterobacteriaceae: Escherichia coli, Yersinia, Salmonella and Shigella. Book chapter in Molecular Typing in Bacterial Infections.
  • Fu, P.P., Chiang, H.M., Xia, Q., Chen, T., Chen, B.H., Yin, J., Wen, K.C., Lin, G., and Yu, H. (2009). Quality assurance and safety of herbal dietary supplements. Journal of Environmental Science and Health, Part C. 27:91-119.
  • Gambus, A., van Deursen, F., Polychronopoulos, D., Foltman, M., Jones, R.C., Edmondson, R.D., Calzada, A., and Labib, K. (2009). A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase alpha within the eukaryotic replisome. EMBO. 28(19):2992-3004.
  • Gao, Y., Holland, R.D., and Yu, L. (2009). Quantitative proteomics for drug toxicity. Briefings in Functional Genomics and Proteomics. 8(2):158-166.
  • Garey, J. and Paule, M.G. (2009). Effects of chronic oral acrylamide exposure on incremental repeated acquisition (learning) task performance in Fischer 344 rats. Neurotoxicology and Teratology. e-pub.
  • George, N. and Chen, J.J. Batch effect estimation of microarray platforms with analysis of variance. Sources and Solutions.
  • Gilbert, K.M., Przybyla-zawislak, B.D., Pumford, N.R., Han, T., Fuscoe, J., Schnackenberg, L., Holland, R.D., Macmillan-Crow, L., Doss, J.C., and Blossom, S.J. (2009). Delineating liver events in trichloroethylene-induced autoimmune hepatitis. Chemical Research in Toxicology. 22:626-632.
  • Gopee, N., Roberts, D.W., Webb, P., Cozart, C., Siitonen, P.H., Latendresse, J.R., Warbritton, A.R., Yu, W.W., Colvin, V.L., Walker, N.J., and Howard, P. (2009). Quantitative determination of skin penetration of PEG-coated CdSe quantum dots in dermabraded but not intact SKH-1 hairless mouse skin. Toxicological Sciences. 111(1):37-48.
  • Guo, L., Li, Q., Xia, Q., Dial, S.L., Chan, P.C., and Fu, P.P. (2009). Analysis of gene expression changes of drug metaboliing enzymes in the livers of F344 rats following oral treatment with kava extract. Food and Chemical Toxicology. 47(2):433-442.
  • Guo, L., Mei, N., Liao, W., Chan, P.C., and Fu, P.P. Ginkgo biloba extract-induced gene expression changes in xenobiotics metabolism and Myc-centered network. OMICS: A Journal of Intergrative Biology.
  • Guo, L., Shi, Q., Fang, J., Mei, N., Ali, A.A., Lewis, S.M., Leakey, J.E., and Frankos, V.H. (2008). Review of usnic acid and Usnea barbata toxicity. Journal of Environmental Science and Health, Part C. 26:317-338.
  • Harel, L., Costa, B., Tcherpakov, M., Zapatka, M., Oberthuer, A., Hansford, L.M., Vojvodic, M., Levy, Z., Chen, Z., Lee, F.S., Avigad, S., Yaniv, I., Shi, L., Eils, R., Fischer, M., Brors, B., Kaplan, D.R., and Fainzilber, M. (2009). CCM2 mediates death signaling by the TrkA receptor tyrosine kinase. Neuron. 63:585-591.
  • He, Z. (2009). Fluorogold induces persistent neurological deficits and circling behavior in mice over-expressing human mutant tau. Current Neurovascular Research. 6(1):54-61.
  • Hong, H. , Shi, L. , Fuscoe, J. , Goodsaid, F.M. , Mendrick, D., and Tong, W. Potential sources of spurious associations and batch effects in genome-wide association studies. Book Chapter in Batch Effect and Experimental Shift in Microarray Analysis: Sources and Solutions.
  • Hong, H., Hong, Q., and Tong, W. (2009). Accurate prediction and recognition of subfamilies of G protein-coupled receptors from amino acid sequences. The 2009 International Conference on Bioinformatics and Computational Biology. 3-9.
  • Hong, H., Hong, Q., Perkins, R.G., Shi, L., Fang, H., Su, Z., Dragan, Y.P., Fuscoe, J., and Tong, W. The accurate prediction of protein family from amino acid sequence by measuring features of sequence fragments. Journal of Computational Biology.
  • Hong, H., Perry, G., Sorgel, F., Gedela, S., and Akulapalli, S. (2009). Editorial: Journal of Bioequivalence & Bioavailability. Journal of Bioequivalence & Availability. 1(1):001-002.
  • Hong, H., Teitel, C.H., James, L.P., Tong, W., Hinson, J.A., Fuscoe, J., and Dragan, Y.P. (2008). SELDI-based proteomic determination of hepatic biomarkers of mouse serum following acetaminophen administration. Journal of Proteomics and Bioinformatics. 1(8):424-436.
  • Il'Yasova, D., McCarthy, B.J., Erdal, S., Shimek, J., Goldstein, J., Doerge, D.R., Myers, S.R., Vineis, P., Wishnok, J.S., Swenberg, J., Bigner, D.D., and Davis, F.G. (2009). Human exposure to selected animal neurocarcinogens: a biomarker-based assessment and implications for brain tumor epidemiology. Journal of Toxicology and Environmental Health, Part B. 12:175-187
  • Jeong, S., Cerniglia, C.E., and Greenlees, K. Avilamycin. 70th Joint FAO/Who Expert Committee on Food Additives.
  • Joseph, A., Lee, T., Moland, C.L., Branham, W.S., Fuscoe, J., Leakey, J.E., Allaben, W.T., Lewis, S.M., Ali, A.A., and Desai, V.G. (2009). Effect of (+)- usnic acid on mitochondrial functions as measured by mitochondria-specific oligonucleotide microarray in liver of B6C3F1 mice. Mitochondrion. 9:149-158.
  • Jung, C.M., Heinze, T.M., Schnackenberg, L., Mullis, L., Elkins, S.A., Elkins, C., Steele, R.S., and Sutherland, J.B. (2009). Interaction of dietary resveratrol with animal-associated bacteria. FEMS Microbiology Letters. 297:266-273.
  • Kaput, J. and Ning, B. (2009). Nutrigenomics for pet nutrition and medicine. Compendium for Continuing Education for the Practicing Veterinarian. 31:40-45.
  • Kaput, J., Chen, J.J. , and Slikker, W. (2009). Personalized nutrition and medicine in perinatal development. Book chapter in Developmental Toxicology, 3rd Edition. Edited by D. Hansen, D and B. Abbott. Published by Informa Heathcare USA. 123-144.
  • Kaput, J., Cotton, R.G., Hardman, L., Watson, M., Al-Aqeel AI, Al-Aama J.Y., Al-Mulla, F., Alonso, S., Aretz, S., Auerbach, A.D., Bapat, B., Bernstein, I.T., Bhak, J., Bleoo, S.L., Blöcker, H., Brenner, S.E., Burn, J., Bustamante, M., Calzone, R., Cambon-Thomsen, A., Cargill, M., Carrera, P., Cavedon, L., Cho, Y.S., Chung, Y.J., Claustres, M., Cutting, G., Dalgleish, R., den Dunnen, J.T., Díaz, C., Dobrowolski, S., dos Santos, M.R., Ekong, R., Flanagan, S.B., Flicek, P., Furukawa, Y., Genuardi, M., Ghang, H., Golubenko, M.V., Greenblatt, M.S., Hamosh, A., Hancock, J.M., Hardison, R., Harrison, T.M., Hoffmann, R., Horaitis, R., Howard, H.J., Barash, C.I., Izagirre, N., Jung, J., Kojima, T., Laradi, S., Lee, Y.S., Lee, J.Y., Gil-da-Silva-Lopes, V.L., Macrae, F.A., Maglott, D., Marafie, M.J., Marsh, S.G., Matsubara, Y., Messiaen, L.M., Möslein, G., Netea, M.G., Norton, M.L., Oefner, P.J., Oetting, W.S., O'Leary, J.C., de Ramirez, A.M., Paalman, M.H., Parboosingh, J., Patrinos, G.P., Perozzi, G., Phillips, I.R., Povey, S., Prasad, S., Qi, M., Quin, D.J., Ramesar, R.S., Richards, C.S., Savige, J., Scheible, D.G., Scott, R.J., Seminara, D., Shephard, E.A., Sijmons, R.H., Smith, T.D., Sobrido, M.J., Tanaka, T., Tanaka, S.V., Taylor, G.R., Teague, J., Töpel, T., Ullman-Cullere, M., Utsunomiya, J., van Kranen, H.J., Vihinen, M., Webb, E., Weber, T.K., Yeager, M., Yeom, Y.I., Yim, S.H., and Yoo, H.S. (2009). Planning the human variome project: the Spain report. Human Mutation. 30:496-510.
  • Kashimshetty, R., Desai, V.G., Kale, V.M., Lee, T., Moland, C.L., Branham, W.S., New, L.S., Chan, E.C., Younis, H., and Boelsterli, U.A. (2009). Underlying mitochondrial dysfunction triggers flutamide-induced oxidative liver injury in a mouse model idiosyncratic drug toxicity. Toxicology and Applied Pharmacology. 238(2):150-159.
  • Khan, A.A., Ponce, E.R., Nawaz, M.S., Cheng, C., Khan, J.A., and Summage-West, C.V. (2009). Identification and characterization of class 1 integron resistance gene cassettes among Salmonella strains isolated from imported seafood. Applied and Environmental Microbiology. 75(4):1192-1196.
  • Khan, S.A., Sung, K., Nawaz, M.S., Cerniglia, C.E., Tamplin, M.L., Phillips, R.W., and Kelley, L.C. (2009). The survivability of Bacillus anthracis (Sterne strain) in processed liquid eggs. Food Microbiology. 26:123-127.
  • Kim, S., Kweon, O., and Cerniglia, C.E. (2009). Proteomic applications to elucidate bacterial aromatic hydrocarbon metabolic pathways. Current Opinion in Microbiology. 12:301-309.
  • Kodell, R.L., Pearce, B.A., Baek, S., Moon, H., Ahn, H., Young, J.F., and Chen, J.J. (2009). A model-free ensemble method for class prediction with application to biomedical decision making. Artificial Intelligence in Medicine. 46(3):267-276.
  • Latendresse, J.R., Bucci, T.J., Olson, G.R., Mellick, P.W., Weis, C.C., Thorn, B.T., Newbold, R., and Delclos, K.B. (2009). Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague-Dawley rats. Reproductive Toxicology. 28(3):342-353.
  • Li, S., Nagothu, K., Desai, V.G., Lee, T., Branham, W.S., Moland, C.L., Megyesi, J., Crew, M., and Portilla, D. Proximal tubule PPARa confers protection during acute kidney injury. Journal of the American Society of Nephrology.
  • Li, Z., Su, Z., Wen, Z., Shi, L., and Chen, T. (2009). Microarray platform consistency is revealed by biologically functional analysis of gene expression profiles. BMC Bioinformatics. 10(11):S12.
  • McBurney, R.N., Hines, W.M., Von Tungeln, L.S., Schnackenberg, L., Beger, R., Moland, C.L., Han, T., Fuscoe, J., Chang, C., Chen, J.J., Su, Z., Fan, X., Tong, W., Booth, S.A., Balasubramanian, R., Courchesne, P.L., Campbell, J.M., Graber, A., Guo, Y, Juhasz, P.J., Li, T.Y., Lynch, M.D., Morel, N.M., Plasterer, T.N., Takach, E.J., Zeng, C., and Beland, F.A. (2009). The liver toxicity biomarker study: phase I design and preliminary results. Toxicologic Pathology. 37(1):52-64.
  • McCabe-Sellers, B.J., Lovera, D., Nuss, H., Wise, C.K., Ning, B., Teitel, C.H., Clark, B.S., Toennessen, T., Green, B.L., Bogle, M.L., and Kaput, J. (2008). Personalizing nutrigenomics research through community-based participatory research and omics technologies. Omics: A Journal of Integrative Biology. 12(4):263-272.
  • Mei, N., Chen, T., Godar, D.E., and Moore, M. (2009). UVA-induced photomutagenicity of retinyl palmitate. Mutation Research/Genetic Toxicology and Environmental Mutagenesis. 677:105-106.
  • Mei, N., Fuscoe, J., Lobenhofer, E.K., and Guo, L. Application of microarray-based analysis of gene expression in the field of toxicogenomics. Book chapter in Rat Genomics: gene identification, functional genomics and model applications.
  • Mei, N., Hu, J., Xia, Q., Fu, P.P., Moore, M., and Chen, T. (2009). Cytotoxicity and mutagenicity of retinol with ultraviolet A irradiation in mouse lymphoma cells. Toxicology In Vitro. e-pub.
  • Melchior, W.B. and Tolleson, W.H. (2010). A functional quantitative PCR assay for ricin, Shiga toxin, and related ribosome-inactivating proteins. Analytical Biochemistry. 396(2):204-211.
  • Meng, F., Knapp, G.W., Green, T., Ross, J., and Parsons, B.L., K-ras mutant fraction in A/J mouse lung increases as a function of benzo[a]pyrene dose. Environmental and Molecular Mutagenesis. e-pub.
  • Millett, C., Yamashita, M., Heller, M., Yu, L., Veenstra, T.D., and Zhang, Y.E. (2009). A negative feedback control of transforming growth factor-beta signaling by glycogen synthase kinase 3-mediated Smad3 linker phosphorylation at Ser-204. Journal of Biological Chemistry. 284(30):19808-19816.
  • Miura, D., Dobrovolsky, V.N., Kimoto, T., Kasahara, Y., and Heflich, R.H. (2009). Accumulation and persistence of PIG-A mutant peripheral red blood cells following treatment of rats with single and split doses of N-ethyl-N-nitrosourea. Mutation Research. 677(1-2): 86-92.
  • Morris, S.M., Dobrovolsky, V.N., Shaddock, J.G., Mittelstaedt, R.A., Bishop, M.E., Manjanatha, M., Shelton, S.D., Doerge, D.R., Twaddle, N.C., Chen, J.J., Lin, Paule, M.G., Slikker, W., Hotchkiss, L., Petibone, D.M., Tucker, J.D., and Mattison, D. (2009). The genetic toxicology of methylphenidate hydrochloride in nonhuman primates. Mutation Research. 673(1):59-66.
  • Myers, M.B., Mittelstaedt, R.A, and Heflich, R.H. (2009). Using ФX174 DNA as an exogenous reference for measuring mitochondrial DNA copy number. BioTechniques. 867-869.
  • Nawaz, M.S., Khan, A.A., Khan, S.A., Sung, K., Kerdahi, K.F., and Steele, R.S. (2009). Molecular characterization of tetracycline-resistant genes and integrons from avirulent strains of Escherichia coli isolates from catfish. Applied and Environmental Microbiology. 6(5):553-559.
  • Parsons, B.L. and Meng, F. K-ras mutation in the screening, prognosis, and treatment of cancer. Biomarkers in Medicine.
  • Patterson, T.A. and Paule, M.G. (2009). Cognitive assessments in nonhuman primates. Book chapter in Fundamentals of Neuropathology for Pathologists and Toxicologists: Principles and Techniques. Edited by Brad Bolon and Mark Butt. J Wiley and Sons, Inc. (In Review).
  • Paule, M.G. (2008). Automated assessment of cognitive function in Macaques. Book chapter in Critical Contributions of Primate Models for Biopharmaceutical Drug Development. Edited by Gerhard Weinbauer and Friedhelm Vogel. Published by Waxman. 113-123.
  • Paule, M.G. (2009). The nonhuman primate as a translational model for pesticide in research. Book Chapter in Hayes’ Handbook of Pesticide Toxicology. Krieger, R., Editor. Elsevier, Inc.
  • Perez-Delacruz, V., Dlinos-Calderon, D., Robledo-Arratia, Y., Medina-Campos, O.N., Pedraza-Chaverri, J., Ali, S.F., and Santamaria, A. (2009). Targeting oxidative/nitrergic stress ameliorates motor impairment, and attenuates synaptic mitochondrial dysfunction and lipid peroxidation in two models of Huntington's disease. Behavioural Brain Research. 199:210-217
  • Pham, A., Wang, J., Fang, J., Gao, X., Zhang, Y., Blower, P.E., Sadee, W., and Huang, Y. (2009). Pharmacogenomics approach reveals MRP1 (ABCC1)-dediated resistance to geldanamycins. Pharmaceutical Research. 26:936-945.
  • Pogribny, I.P. (2009). Genomic instability induced by heat-inactivated bacteria: implication to tumorigenesis. Cell Cycle. 8(13): 1983.
  • Pogribny, I.P. and Beland, F.A. (2009). DNA hypomethylation in the origin and pathogenesis of human diseases. Cellular and Molecular Life Sciences. 66(14):2249-2261.
  • Pogribny, I.P., Muskhelishvili, L., Tryndyak, V.P., and Beland, F.A. (2009). The tumor-promoting activity of 2-acetylaminofluorene is associated with disturbed p53 signaling pathway and disrupted balance between apoptosis and cell proliferation. Toxicolology and Applied Pharmacology. 235(3):305-311.
  • Pogribny, I.P., Shpyleva, S.I., Muskhelishvili, L., Bagnyukova, T.V., James-Gaylor, J.S., and Beland, F.A. (2009). Role of DNA damage and alterations in cytosine DNA methylation in rat liver carcinogenesis induced by a methyl-deficient diet. Mutation Research. 669(1-2):56-62.
  • Pogribny, I.P., Tryndyak, V.P., Bagnyukova, T.V., Melnyk, S.B., Montgomery, B.A., Ross, S., Latendresse, J.R., Rusyn, I., and Beland, F.A. (2009). Hepatic epigenetic phenotype predetermines individual susceptibility to hepatic steatosis in mice fed a lipogenic methyl-deficient diet. Journal of Hepatology. 51(1):176-186.
  • Rafii, F., Park, M., and Carman, R.J. (2009). Characterization of an ATP binding cassette from Clostridium perfringens with homology to an ABC transporter from Clostridium hathewayi. Anaerobe. 15:116-121.
  • Rafii, F., Sutherland, J.B., and Cerniglia, C.E. (2008). Effects of treatment with antimicrobial agents on the human colonic microflora. Therapeutics and Clinical Risk Management. 4(6):1343-1358.
  • Rafii, F., Williams, A.J., Park, M., Sims, L.M., Heinze, T.M., Cerniglia, C.E., and Sutherland, J.B. (2009). Isolation of bacterial strains from bovine fecal microflora capable of degradation of ceftiofur. Veterinary Microbiology. 139(1-2):89-96.
  • Rahman, M.F., Schrand, A., Hussain, S., Schlager, J., Smith, D., and Ali, S.F. Metallic nanoparticles and their toxicity assessment. Nanomedicine and Nanobiothenology.
  • Rahman, M.F., Wang, J., Patterson, T.A., Saini, U.T., Robinson, B.L., Newport, G.D., Murdock, R.C., Schlager, J.J., Hussain, S.M., and Ali, S.F. (2009). Expression of genes related to oxidative stress in the mouse brain after exposure to silver-25 nanoparticles. Toxicological Letters. 187:15-21.
  • Ray, P., Yu, H., and Fu, P.P. (2009). Toxicity and environmental risks of nanomaterials: challenges and future needs. Journal of Environmental Science and Health, Part C. 27:1-35.
  • Ritter, L., Nichol, K., Kirby, G., Cerniglia, C.E., Bulder, A., and Anadon, A. Monensin. 70th Joint FAO/WHO Expert Committee on Food Additives.
  • Roberts, G., Cerniglia, C.E., and Neto, J.P. Tylosin. 70th Joint FAO/WHO Expert Committee on Food Additives.
  • Rosas-Hernandeez, H., Jiménez-Badillo, S., Martinez-Cuevas, P., Gracia-Espino, E., Terrones, H., Terrones, M., Hussain, S., Ali, S.F. , and Gonzalez, C. (2009). Effects of 45-nm silver nanoparticles on coronary endothelial cells and isolated rat aortic rings. Toxicological Letters. 191:305-313.
  • Schmued, L.C., Bowyer, J.F., Cozart, M.A., Heard, D.W., Binienda, Z.K., and Paule, M.G. (2008). Introducing Black-Gold II, a highly soluble gold phosphate complex with several unique advantages for the histochemical localization of myelin. Brain Research. 1229:210-217.
  • Schnackenberg, L. and Mendrick, D. (2009). Genomic and metabolomic advances in the indentification of disease and adverse event biomarkers. Biomarkers in Medicine. 3(5):605-615.
  • Schnackenberg, L., Chen, M., Sun, J., Holland, R.D., Dragan, Y.P., Tong, W., Welsh, W.J., and Beger, R. (2009). Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. Toxicology and Applied Pharmacology. 235:25-32.
  • Sharma, H. Ali, S.F. , Hussain, S., Schlager, J., and Sharma, A. (2009). Influence of engineered nanoparticles from metals on the blood-brain barrier permeability, cerebral blood flow, brain edema and neurotoxicity. An experimental study in the rat and mice using biochemical and morphological approaches. Journal of Nanoscience and Nanotechnology. 9(8):5055-5072.
  • Sharma, H., Ali, S.F. , Tian, Z.R., Hussain, S. Schlager, J., Sjöquist P.O., Sharma A., and Muresanu, D.F. (2009). Chronic treatment with nanoparticles exacerbate hyperthermia induced blood-barrier breakdown, cognitive dysfunction and brain pathology in the rat. Neuroprotective effects of nanowired-antioxidant compound H-290/51. Journal of Nanoscience and Nanotechnology. 5073-5090.
  • Smeltzer, M.S., Lee, C.Y., Harik, N., and Hart, M.E. The molecular basis of pathogenicity. Book chapter in The Staphylococci in Human Disease. Edited by Crossley, Archer, Fowler, and Jefferson. Published by Blackwell Publishing, Ltd.
  • Smith, M.E., Gopee, N., and Ferguson, S.A. (2009). Preferences of minipigs for environmental enrichment objects. Journal of the American Association of Laboratory Animal Science. 48:391-394.
  • Soung, N., Park, J. , Yu, L. , Lee, K.H. , Lee, J. , Bang, J.K. , Veenstra, T.D. , Rhee, K. , and Lee, K.S. (2009). Plk1-dependent and -independent roles of an ODF2 splice variant, hCenexin1, at the centrosome of somatic cells. Developmental Cell. 16(4):539-550.
  • Stewart, G., Jias, Y., Valente, E., Fu, P.P., Li, T., Hu, Z., and Yu, H. (2009). Photochemical reaction of 9-nitro-substituted anthracene-like molecules 9-methyl-10-nitroanthracene and 12-methyl-7-nitrobenz[a]anthracene. Journal of Photochemistry and Photobiology A: Chemistry. 201:39-44.
  • Stingley, R.L., Zou, W., Heinze, T.M., Chen, H., and Cerniglia, C.E. (2009). Metabolism of azo dyes by human skin microbiota. Journal of Medical Microbiology. e-pub.
  • Sun, J. and Lynn, B.C. (2009). Development of a LC/MS/MS method to analyze butyrylcholinesterase inhibition resulting from multiple pesticide exposure. Journal of Chromatography B. 877(29):3681-3685.
  • Sun, J., Schnackenberg, L., and Beger, R. (2009). Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. Drug Metabolism Letters. 3(3):130-136.
  • Sun, J., Von Tungeln, L.S., Hines, W.M., and Beger, R. (2009). Identification of metabolite profiles of the catechol-O-methyl transferase inhibitor tolcapone in rat urine using LC/MS-based metabonomics analysis. Journal of Chromtography B. 877(24):2557-2565.
  • Tareke, E., Heinze, T.M., Gamboa da Costa, G., and Ali, S. (2009). Acrylamide formed at physiological temperature as a result of asparagine oxidation. Journal of Agricultural and Food Chemistry. 57(20): 9730-9733.
  • Tareke, E., Lyn-Cook, B.A., Duhart, H.M., Newport, G.D., and Ali, S.F. (2009). Acrylamide decreased dopamine levels and increased 3-nitrotyrosine (3-NT) levels in PC-12 cells. Neuroscience Letters. 458(2):89-92.
  • Thomas, M., George, N.I., Patterson, T.A., and Bowyer, J.F. (2009). Amphetamine and environmentally induced hyperthermia differentially alter the expression of genes regulating vascular tone and angiogenesis in the meninges and associated vasculature. Synapse. 63(10):881-894.
  • Tolleson, W.H. (2008). Melanin and neuromelanin in the nervous system. Book chapter in Encyclopedic Reference of Neuroscience. 2288-2294. Edited by John J. Haddad, Ph.D.
  • Tolleson, W.H. Renal toxicity of pet foods contaminated with melamine and related compounds. Proceedings of the ACS Symposium on Intentional and Unintentional Contaminants of Food and Feed.
  • Tong, W., Fang, H., and Mendrick, D. (2009). Toxicogenomics and cell-based assays for toxicology. Interdisciplinary Bio Central Journal. 1(3):10-15.
  • Tryndyak, V.P., Beland, F.A., and Pogribny, I.P. (2009). E-cadherin transcriptional down-regulation by epigenetic and microRNA-200 family alterations is related to mesenchymal and drug-resistant phenotypes in human breast cancer cells. International Journal of Cancer. e-pub.
  • van Ommen, B., Keijer, J., Heil, S., and Kaput, J. (2009). Challenging homeostasis to define biomarkers for nutrition related health. Molecular Nutrition and Food Research. 53(7):795-804.
  • Von Tungeln, L.S., Churchwell, M.I., Doerge, D.R., Shaddock, J.G., McGarrity, L.J., Heflich, R.H., Gamboa Da Costa, G., Marques, M.M., and Beland, F.A. (2009). DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide. International Journal of Cancer. 124(9):2006-2015.
  • Wang, J., Sawyer, J.R., Chen, L., Chen, T., Honma, M., Mei, N., and Moore, M. (2009). The mouse lymphoma assay detects recombination, deletion, and aneuploidy. Toxicological Sciences. 109(1):96-105.
  • Wang, J.C. and Chen, T. (2009). Sequencing analysis of mutations induced by N-ethyl-N-nitrosourea at different sampling times in mouse bone marrow. Journal of Applied Toxicology. e-pub.
  • Wang, L., Wang, S., Yin, J., Wang, Z., Fu, P.P., and Yu, H. (2009). Light-induced toxic effects of tamoxifen: a chemotherapeutic and chemopreventive agent. Journal of Photochemistry and Photobiology A: Chemistry. 201:50-56.
  • Wise, C.K. and Kaput, J. (2009). A strategy for analyzing gene-nutrient interactions in type 2 diabetes. Journal of Diabetes Science and Technology. 3(4):710-721.
  • Xu, H., Heinze, T.M., Paine, D.D., Cerniglia, C.E., and Chen, H. (2009). Sudan azo dyes and Para Red degradation by prevalent bacteria of the human gastrointestinal tract. Anaerobe. e-pub.
  • Yin, J., Lao, F. Fu, P.P., Wamer, W., Zhao, Y. Wang, P.C., Qiu, Y., Sun, B., Xing, G., Dong, J., Liang, X., and Chen, C. (2009). The scavenging of reactive oxygen species and the potential for cell protection by functionalized fullerene materials. Biomaterials. 30(4):611-621.
  • Young, J.F., Luecke, R., Pearce, B.A., Lee, T., Ahn, H., Baek, S., Moon, H., Dye, D.W., Davis, T.M., and Taylor, S.H. (2009). Human organ/tissue growth algorithms that include obese individuals and black/white population organ weight similarities from autopsy data. Journal of Toxicology and Environmental Health, Part A. 72(8):527-40.
  • Zhang, X. and Paule, M.G. Neurotoxicant-induced animal models of neurological disorders. Book chapter in In Vivo Systems: Animal Models of Neurological Diseases.
  • Zhang, X., Paule, M.G., Newport, G.D.D., Zou, X., Sadovova, N., Berridge, M.S., Apana, S.M., Hanig, J.P., Slikker, W., Jr., and Wang, C., (2009). A minimally invasive, translational biomarker of ketamine-induced neuronal death in rats: microPET imaging using [18F]-annexin V. Toxicological Science. 111:355-361.
  • Zhu, J., Xu, W., Wang, J., Ali, S.F., and Angulo, J. (2009). The neurokinin-1 receptor modulates the methamphetamine-induced striatal apoptosis and nitric oxide formation in mice. Journal of Neurochemistry. 111:656-668.
  • Zou, W., Cerniglia, C.E., and Chen, H. Azoreductase in Staphylococcus aureus. Current Protocols in Toxicology.
  • Zou, W., Frye, J.G., Chang, C., Liu, J., Cerniglia, C.E., and Nayak, R.R. (2009). Microarray analysis of antimicrobial-resistance genes in Salmonella enterica from preharvest poultry environment. Journal of Applied Microbiology. 107(3):906-914.
  • Zou, X., Patterson, T.A., Divine, B., Sadovova, N., Zhang, X., Paule, M.G., Slikker, W. Jr., Hanig, J., and Wang, C. (2009). Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain. International Journal of Developmental Neurscience. 27(7):727-731.
  • Zou, X., Patterson, T.A., Sadovova, N.V., Twaddle, N.C., Doerge, D.R., Zhang, X., Fu, X., Hanig, J.P., Paule, M.G., Slikker, W., and Wang, C. (2009). Potential neurotoxicity of ketamine in the developing rat brain. Toxicological Sciences. 108(1):149-158.
 

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