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NTP Center for Phototoxicology Publications

Publication Year 
  2008 2007 2006 2005 2004 2003 2002 2001  

 

2008
  • Boudreau, M.D. 2008. National Toxicology Program. Photococarcinogenesis Study of Aloe vera in SKH-1 mice. Technical Report Series, no.553. NIH Publication No. 08-5894. U.S. Department of Health and Human Services. Public Health Service. National Institutes of Health, Research Triangle Park, NC.
  • Verkler, T.L., Delongchamp, R.R., Couch, L.H., Miller, B.J., Warbritton, A., Mellick, P.W., Howard, P.C., and Parsons, B.L. 2008. Populations of p53 codon 270 CGT to TGT mutant cells in SKH-1 mouse skin tumors induced by simulated solar light. Molecular Carcinogenesis. 47:822-834.
  • Verkler, T.L., Delongchamp, R.R., Miller, B.J., Webb, P.J., Howard, P.C., and Parsons, B.L. 2008. Simulated solar light-induced p53 mutagenesis in SKH-1 mouse skin: a dose-response assessment. Molecular Carcinogenesis. 47:599-607.

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2007
  • Fu, P., Xia, Q., Boudreau, M.D., Howard, P.C., Tolleson, W., and Wamer, W. 2007. Physiological role of retinyl palmitate in the skin. In Vitamins and Hormones.   75:223-256. G. Litwack (Editor). Academic Press, Elsevier Inc., San Diego, CA.
  • Fu, P., Xia, Q., Yin, J.J., Cherng, S., Yan, J., Mei, N., Chen, T., Boudreau, M.D., Howard, P.C., and Wamer, W.G. 2007. Photodecomposition of vitamin A and photobiological implications for the skin. Photochemistry and Photobiology. 83:409-424.
  • Gopee, N.V., and Howard, P.C. 2007. A time-course study demonstrating RNA stability in postmortem skin. Experimental and Molecular Pathology. 83:4-10.
  • Gopee, N.V., Roberts, D.W., Cozart, C., Siitonen, P.H., Walker, N.J., Yu, W.W., Colvin, V.L., and Howard, P.C. 2007. Migration of intradermally injected quantum dots to sentinel organs in mice. Toxicological Sciences. 98:249-257.
  • Xia, Q., Yan, J.J., Fu, P.P., and Boudreau, M.D. 2007. Photo-irradiation of Aloe vera by UVA—formation of free radicals, singlet oxygen, superoxide and induction of lipid peroxidation. Toxicology Letters. 168:165-175.

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2006
  • Boudreau, M.D., and Beland, F.A. 2006. An evaluation of the biological and toxicological properties of Aloe Barbadensis (Miller), Aloe Vera.Journal of Environmental Science and Health Part C. 24:103-154.
  • Howard, P.C. 2006. National Toxicology Program. Photocarcinogenesis study of glycolic acid and salicylic acid in SKH-1 mice (simulated solar light and topical application studies). Technical Report Series, no.524. NIH Publication No. 05-4472. U.S. Department of Health and Human Services. Public Health Service. National Institutes of Health. Research Triangle Park, NC.
  • Tsuji, J.S., Maynard, A.D., Howard, P.C., James, J.T., Lam, C.W., Warheit, D.B., and Santamaria, A.B. 2006. Research strategies for safety evaluation of nanomaterials, Part IV: risk assessment of nanoparticles. Toxicological Sciences. 89:42-50.
  • Xia, Q., Chou, M.W., Yin, J.J., Howard, P.C. and P.P. Fu. 2006. Photoirradiation of representative polycyclic aromatic hydrocarbons and twelve isomeric methylbenz[a]anthracene with UVA light: formation of lipid peroxidation. Toxicology and Industrial Health. 22:147-156.
  • Xia, Q., Yan, J.J., Cherng, S.-H., Wamer, W.C., Boudreau, M., Howard, P.C., and Fu, P.P. 2006. UVA photoirradiation of retinyl palmitate–formation of singlet oxygen and superoxide, and their role in induction of lipid peroxidation. Toxicology Letters. 163:30-43.
  • Xia, Q., Yin, J.J, Wamer, W.G., Cherng, S.-H., Boudreau, M., Howard, P.C., Yu, H., and Fu, P.P. 2006. Photoirradiation of retinyl palmitate in ethanol with ultraviolet light–formation of photodecomposition products, reactive oxygen species, and lipid peroxides. International Journal of Environmental Research and Public Health. 3(2):185-190.
  • Yan, J., Wamer, W.G., Howard, P.C., Boudreau, M. and Fu, P.P. 2006. Levels of retinyl palmitate and retinol in stratum corneum, epidermis, and dermis of female SKH-1 mice topically treated with retinyl palmitate. Toxicology and Industrial Health. 22:181-191.
  • Yan, J., Xia, Q., Webb, P., Warbritton, A.R., Wamer, W.G., Howard, P.C., Boudreau, M., and Fu, P.P. 2006. Levels of retinyl palmitate and retinol in stratum corneum, epidermis, and dermis of SKH-1 mice. Toxicology and Industrial Health. 22:103-112.

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2005
  • Cherng, S.-H., Xia, Q., Blakenship, L.R., Freeman, J.P., Wamer, W.G., Howard, P.C., and Fu, P.P. 2005. Photodecomposition of retinyl palmitate in ethanol by UVA light–formation of photodecomposition products, reactive oxygen species, and lipid peroxides. Chemical Research in Toxicology. 18:129-138.
  • Cui, Y., Churchwell, M.I., Couch, L.H., Doerge, D.R., and Howard, P.C. 2005. Metabolism of pigment yellow 74 by rat and human microsomal proteins. Drug Metabolism and Disposition. 33:1459-1465.
  • Gopee, N.V., Cui, Y., Olson, G., Warbritton, A.R., Miller, B.J., Couch, L.H., Wamer, W.G., and Howard, P.C. 2005. Response of mouse skin to tattooing: use of SKH-1 mice as a surrogate model for human tattooing. Toxicology and Applied Pharmacology. 209:145-158.
  • Molefe, D., Chen, J.J., Howard, P.C., Miller, B.J., Sambuco, C.P., Forbes, P.D. and Kodell, R.L. 2005. Tests for effects on tumor frequency and latency in multiple dosing photococarcinogenicity experiments. Journal of Statistical Planning and Inference. 129:35-58.
  • Tolleson, W.H., Cherng, S.H., Xia, Q., Boudreau, M., Yin, J.J., Wamer, W.G., Howard, P.C., Yu, H., and Fu, P.P. 2005. Photoreaction, phototoxicity, and photocarcinogenicity of retinoids. International Journal of Environmental Research and Public Health. 2:147-55.
  • Tsuji, J.S., Maynard, A.D., Howard, P.C., James, J.T., Lam, C.W., Warheit, D.B., and Santamaria, A.B. 2005. Research Strategies for safety evaluation of nanomaterials, part IV: risk assessment of nanoparticles. Toxicological Sciences. 89:42-50.
  • Verkler, T.L., Couch, L.H., Howard, P.C., and Parsons, B.L. 2005. Quantifying levels of p53 mutation in mouse skin tumors. Environmental and Molecular Mutagenesis. 45:427-434.
  • Yan, J., Xia, Q., Cherng, S.H., Wamer, W.G., Howard, P.C., Yu, H., and Fu, P.P. 2005. Photo-induced DNA damage and photocytotoxicity of retinyl palmitate and its photodecomposition products. Toxicology and Industrial Health. 21:167-175.

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2004
  • Cui, Y., Spann, A.P., Couch L.H., Gopee, N.V., Evans, F.E., Churchwell, M.I., Williams, L.D., Doerge, D.R., and Howard, P.C. 2004. Photodecomposition of pigment yellow 74, a pigment used in tattoo inks. Photochemistry and Photobiology, 80:175-84.
  • Molefe, D., Chen, J.J. Howard, P.C. Miller, B.J., Sambuco, C.P., Forbes, P.D. and Kodell, R.L. 2004. Tests for effects on tumor frequency and latency in multiple dosing photococarcinogenicity experiments. Journal of Statistical Planning and Inference. 129:39-58.

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2003
  • Fu, P.P., Cherng, S.-H., Coop, L., Xia, Q., Culp, S.J., Tolleson, W.H., Wamer, W.G., and Howard, P.C. 2003. Photoreaction, phototoxicity and photocarcinogenicity of retinoids. Environmental Carcinogens and Ecotoxicology Reviews. C21:165-197.

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2002
  • Couch. L.H., and Howard, P.C.. 2002. Quantification of glycolic acid in cosmetic products using reversed phase high performance liquid chromatography. International Journal of Cosmetic Science. 24:89-95.
  • Fu, P., Howard, P.C., Culp, S.J., Xia, Q., Webb, P.J., Blankenship, L.R. Wamer, W.G. and Bucher, J.R. 2002. Do topically applied skin creams containing retinyl palmitate affect the photocarcinogenicity of simulated solar light? Journal of Food and Drug Analysis. 10:262-268.
  • Howard, P.C., Sams R.L.,II, Dennis, D.A. and Wamer, W.G. 2002. Alpha-hydroxy acids: consideration of the biological effects and possible role in photococarcinogenesis. Journal of Food and Drug Analysis. 10:258-261.
  • Howard, P.C., Sams, R.L.,II, Bucher, J.R. and Allaben, W.T. 2002. Phototoxicology and photocarcinogenesis at the U.S. Food and Drug Administration’s National Center for Toxicological Research. Journal of Food and Drug Analysis. 10:252-257.
  • Sams, R.L.,II, Couch, L.H., Miller, B.J. Okerberg, C.V., Warbritton, A.R. Wamer, W.G., Beer, J.Z. and Howard, P.C. 2002. The effects of alpha- and beta-hydroxy acids on the edemal response induced in female SKH-1 mice by simulated solar light. Toxicology and Applied Pharmacology. 184:136-143.

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2001
  • Sams, R.L., II, Couch, L.H. Miller, B.J. Okerberg, c.V. Warbritton, A. Wamer, W.G., Beer, J.Z. and Howard, P.C. 2001. Basal cell proliferation in female SKH-1 mice treated with alpha- and beta-hydroxy acids. Toxicology and Applied Pharmacology. 175:76-82.

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